SGLT2 Inhibitor: Not a Traditional Diuretic for Heart Failure

Verma Ashish; Patel Ankit B.; Waikar Sushrut S.

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SGLT2 Inhibitor: Not a Traditional Diuretic for Heart Failure

机译：SGLT2抑制剂：不是一种传统的心力衰竭利尿剂

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Recent studies have shown impressive cardiovascular health benefits in individuals treated with SGLT2 inhibitors (SGLT2i) regardless of diabetic status. The underlying mechanisms driving these benefits are not well understood. Recently in Circulation, Griffin et al. (2020) reported the first human study investigating the diuretic effect of empagliflozin.

机译：最近的研究表明，无论糖尿病状态如何，用SGLT2抑制剂（SGLT2i）处理的个体心血管健康益处令人印象深刻的心血管健康益处。推动这些益处的潜在机制并不是很好地理解。最近在流通，格里芬等人。（2020）报道了研究Empagliflozin的利尿作用的第一个人类研究。

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《Cell metabolism》 |2020年第1期|共2页
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Verma Ashish; Patel Ankit B.; Waikar Sushrut S.;
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Brigham &

Womens Hosp Dept Med Div Renal Boston MA 02115 USA;

Brigham &

Womens Hosp Dept Med Div Renal Boston MA 02115 USA;

Boston Univ Sch Med Dept Med Nephrol Sect Boston MA 02118 USA;

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正文语种 eng
中图分类内分泌腺疾病及代谢病;
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1. SGLT2 Inhibitor: Not a Traditional Diuretic for Heart Failure [J] . Verma Ashish, Patel Ankit B., Waikar Sushrut S. Cell metabolism . 2020,第1期

机译：SGLT2抑制剂：不是一种传统的心力衰竭利尿剂
2. Renal and Cardiovascular Effects of sodium?￠??glucose cotransporter 2 (SGLT2) inhibition in combination with loop Diuretics in diabetic patients with Chronic Heart Failure (RECEDE-CHF): protocol for a randomised controlled double-blind cross-over trial [J] . Allan D Struthers, Rory J McCrimmon, Jagdeep S Singh, BMJ Open . 2017,第10期

机译：慢性心力衰竭的糖尿病患者中钠￠γ葡萄糖共转运蛋白2（SGLT2）抑制与环利尿剂联用对肾脏和心血管的影响：一项随机对照双盲交叉试验的方案
3. Renal and Cardiovascular Effects of sodium?￠??glucose cotransporter 2 (SGLT2) inhibition in combination with loop Diuretics in diabetic patients with Chronic Heart Failure (RECEDE-CHF): protocol for a randomised controlled double-blind cross-over trial [J] . Allan D Struthers, Rory J McCrimmon, Jagdeep S Singh, BMJ Open . 2017,第10期

机译：慢性心力衰竭的糖尿病患者中钠￠γ葡萄糖共转运蛋白2（SGLT2）抑制与环利尿剂联用对肾脏和心血管的影响：一项随机对照双盲交叉试验的方案
4. DIURETIC RESISTANCE IN DOGS TREATED FOR HEART FAILURE [C] . Mark A. Oyama American College of Veterinary Internal Medicine Forum . 2012

机译：治疗心力衰竭治疗的狗的利尿耐药性
5. Getting to the Heart of the Matter: Clinical Inertia Slows SGLT2 Inhibitor Prescribing Rates in Patients with T2D and Concurrent ASCVD [D] . Scott, Joshua Seth. 2019

机译：达到此事的核心：临床惯性减缓了T2D和同时ASCVD患者的SGLT2抑制剂处方率
6. Comparative effectiveness of canagliflozin SGLT2 inhibitors and non‐SGLT2 inhibitors on the risk of hospitalization for heart failure and amputation in patients with type 2 diabetes mellitus: A real‐world meta‐analysis of 4 observational databases (OBSERVE‐4D) [O] . Patrick B. Ryan, John B. Buse, Martijn J. Schuemie, -1

机译：卡那列净SGLT2抑制剂和非SGLT2抑制剂对2型糖尿病患者心衰和截肢住院风险的比较有效性：4个观察性数据库的真实荟萃分析（OBSERVE-4D）
7. Correction to: Renal and Cardiovascular Effects of SGLT2 Inhibition in Combination with Loop Diuretics in Patients with Type 2 Diabetes and Chronic Heart Failure: The RECEDE-CHF Trial [O] . 2020

机译：校正：患有2型糖尿病和慢性心力衰竭患者的肾脏和心血管抑制的肾和心血管作用与环路利尿剂相结合，慢性心力衰竭：RECED-CHF试验

SGLT2 Inhibitor: Not a Traditional Diuretic for Heart Failure

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