When Soluble Fibers Meet Hepatocellular Carcinoma: The Dark Side of Fermentation

Gallage Suchira; Kotsiliti Elena; Heikenwalder Mathias

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When Soluble Fibers Meet Hepatocellular Carcinoma: The Dark Side of Fermentation

机译：当可溶性纤维达到肝细胞癌时：发酵的黑暗面

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Fermentation of dietary soluble fibers by our gut microbiota generates short-chain fatty acids (SCFAs) and metabolites, upholding health and being a valuable food supplement. Recently, in Cell, Singh et al. (2018) discovered that fermentable, dietary soluble fibers (e.g., inulin) induced cholestasis and hepatocellular carcinoma (HCC) while improving metabolic dysfunction.

机译：我们的肠道微生物酵母发酵膳食可溶性纤维产生短链脂肪酸（SCFA）和代谢物，维护健康，是有价值的食品补充剂。最近，在Cell，Singh等人。（2018）发现可发酵，膳食可溶性纤维（例如，菊粉）诱导的胆汁淤积和肝细胞癌（HCC），同时改善代谢功能障碍。

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《Cell metabolism》 |2018年第5期|共3页
作者
Gallage Suchira; Kotsiliti Elena; Heikenwalder Mathias;
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German Canc Res Ctr Div Chron Inflammat &

Canc Neuenheimer Feld 242 D-69120 Heidelberg Germany;

German Canc Res Ctr Div Chron Inflammat &

Canc Neuenheimer Feld 242 D-69120 Heidelberg Germany;

German Canc Res Ctr Div Chron Inflammat &

Canc Neuenheimer Feld 242 D-69120 Heidelberg Germany;

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正文语种 eng
中图分类内分泌腺疾病及代谢病;
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1. When Soluble Fibers Meet Hepatocellular Carcinoma: The Dark Side of Fermentation [J] . Gallage Suchira, Kotsiliti Elena, Heikenwalder Mathias Cell metabolism . 2018,第5期

机译：当可溶性纤维达到肝细胞癌时：发酵的黑暗面
2. Highly elevated soluble Tim-3 levels correlate with increased hepatocellular carcinoma risk and poor survival of hepatocellular carcinoma patients in chronic hepatitis B virus infection [J] . Fang Li, Na Li, Jiao Sang, Cancer Management and Research . 2018,第2013期

机译：可溶性Tim-3的高度升高与慢性乙型肝炎病毒感染的肝细胞癌风险增加和肝细胞癌患者生存不良有关
3. Expanding the Liver Imaging Reporting and Data System (LI-RADS) v2018 diagnostic population: performance and reliability of LI-RADS for distinguishing hepatocellular carcinoma (HCC) from non-HCC primary liver carcinoma in patients who do not meet strict LI-RADS high-risk criteria [J] . Ludwig Daniel R., Fraum Tyler J., Cannella Roberto, HPB: the official journal of the International Hepato Pancreato Biliary Association . 2019,第12期

机译：扩大肝脏成像报告和数据系统（LI-RADS）V2018诊断群：LI-RAD的性能和可靠性，以区分肝细胞癌（HCC）从非HCC原发性肝癌中不符合严格LI-RAD的患者风险标准
4. Soluble E-Selectin and Hyaluronic Acid as Tumor Markers for Hepatocellular Carcinoma [C] . Wickham N. West D, Ho S, Leung WT, NATO Advanced Study Institute on Vascular Endothelium : Mechanisms of Cell Signaling . 1999

机译：可溶性E-SELETIN和透明质酸作为肝细胞癌的肿瘤标志物
5. Fermentation characteristics of native soluble fiber sources by human colonic bacteria [D] . Yobi, Abou 2004

机译：人类结肠细菌对天然可溶性纤维来源的发酵特性
6. Highly elevated soluble Tim-3 levels correlate with increased hepatocellular carcinoma risk and poor survival of hepatocellular carcinoma patients in chronic hepatitis B virus infection [O] . Fang Li, Na Li, Jiao Sang, 2018

机译：可溶性Tim-3水平的升高与慢性乙型肝炎病毒感染的肝细胞癌风险增加和肝细胞癌患者生存不良有关
7. Comparison of Different Soluble Dietary Fibers during the In Vitro Fermentation Process [O] . -1

机译：在体外发酵过程中不同可溶性膳食纤维的比较

When Soluble Fibers Meet Hepatocellular Carcinoma: The Dark Side of Fermentation

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