SERCA2b Cycles Its Way to UCP1-Independent Thermogenesis in Beige Fat

Mottillo Emilio P.; Ramseyer Vanesa D.; Granneman James G.

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SERCA2b Cycles Its Way to UCP1-Independent Thermogenesis in Beige Fat

机译：Serca2b在米色脂肪中循环到UCP1独立的热生成的途径

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A new study in Nature Medicine, by Ikeda et al. (2017), reports that calcium cycling in beige adipocytes elevates energy expenditure and glucose oxidation in the absence of uncoupling protein 1. Thermogenic calcium cycling in beige fat is mediated by SERCA2b and improves cold tolerance and metabolic status.

机译：Ikeda等人的自然医学研究。（2017），报道：米黄脂肪细胞中的钙循环循环升高了能量消耗和葡萄糖氧化在没有解耦蛋白1.米色脂肪中的热钙循环由Serca2b介导，提高了耐寒性和代谢状态。

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《Cell metabolism》 |2018年第1期|共4页
作者
Mottillo Emilio P.; Ramseyer Vanesa D.; Granneman James G.;
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作者单位

Wayne State Univ Sch Med Ctr Integrat Metab &

Endocrine Res Detroit MI 48202 USA;

Wayne State Univ Sch Med Ctr Integrat Metab &

Endocrine Res Detroit MI 48202 USA;

Wayne State Univ Sch Med Ctr Integrat Metab &

Endocrine Res Detroit MI 48202 USA;

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正文语种 eng
中图分类内分泌腺疾病及代谢病;
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1. SERCA2b Cycles Its Way to UCP1-Independent Thermogenesis in Beige Fat [J] . Mottillo Emilio P., Ramseyer Vanesa D., Granneman James G. Cell metabolism . 2018,第1期

机译：Serca2b在米色脂肪中循环到UCP1独立的热生成的途径
2. UCP1-independent signaling involving SERCA2b-mediated calcium cycling regulates beige fat thermogenesis and systemic glucose homeostasis [J] . Ikeda Kenji, Kang Qianqian, Yoneshiro Takeshi, Nature medicine . 2017,第12期

机译：UCP1无关信号涉及Serca2B介导的钙循环调节米色脂肪热生成和全身葡萄糖稳态
3. A Creatine-Driven Substrate Cycle Enhances Energy Expenditure and Thermogenesis in Beige Fat [J] . Kazak Lawrence, Chouchani Edward T., Jedrychowski Mark P., Cell . 2015,第3期

机译：肌酸驱动的底物循环增强了米色脂肪的能量消耗和生热作用
4. Improving cardiac Ca~(2+) transport into the sarcoplasmic reticulunn in heart failure: lessons from the ubiquitous SERCA2b Ca~(2+) pump [C] . Peter Vangheluwe, Frank Wuytack Biochemical Society Annual Symposium . 2011

机译：将心脏Ca〜（2+）输送到心力衰竭中的肌淋式reticulunn中：普遍存在的Serca2b Ca〜（2+）泵的课程
5. Octacosanol prevents high fat diet-induced obesity by activating energy expenditure and thermogenesis in brown and beige fats [D] . Rahul Sharma 2019

机译：十八碳烷醇可通过激活棕色和米色脂肪中的能量消耗和生热作用来预防高脂饮食引起的肥胖
6. UCP1-independent signaling involving SERCA2b-mediated calcium cycling regulates beige fat thermogenesis and systemic glucose homeostasis [O] . Kenji Ikeda, Qianqian Kang, Takeshi Yoneshiro, -1

机译：涉及SERCA2b介导的钙循环的UCP1独立信号调节米色脂肪生热和系统性葡萄糖稳态
7. A Creatine-Driven Substrate Cycle Enhances Energy Expenditure and Thermogenesis in Beige Fat [O] . Kazak Lawrence, Chouchani Edward T., Jedrychowski Mark P., 2015

机译：肌酸驱动的底物循环增强了米色脂肪的能量消耗和生热作用

SERCA2b Cycles Its Way to UCP1-Independent Thermogenesis in Beige Fat

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