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首页> 外文期刊>Acta ophthalmologica >The decline in visual acuity in elderly people with healthy eyes or eyes with early age-related maculopathy in two Scandinavian population samples.
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The decline in visual acuity in elderly people with healthy eyes or eyes with early age-related maculopathy in two Scandinavian population samples.

机译：在两个斯堪的纳维亚人口样本中，健康眼睛的老年人或早期与年龄相关的黄斑病变的眼睛的视力下降。

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Purpose: This study aimed to analyse the decline in visual acuity (VA) during normal ageing in two Scandinavian population samples of subjects aged >/= 70 years and to study the age-specific decline in VA in eyes with early age-related maculopathy (ARM). Methods: We carried out a cross-sectional analysis of data pertaining to VA in the better eye in one population sample from Oulu (OU), Finland (aged 70-82 years) and a second population sample from Gothenburg (GG), Sweden (aged 82 or 88 years). The change in VA with age was evaluated in healthy eyes (OU, n = 119; GG, n = 40) and in eyes with early ARM (OU-ARM, n = 22; GG-ARM, n = 114) using linear regression or logistic regression. The results were compared with those of previous reports. Results: Our population samples showed a significant decrease with age in VA in healthy eyes in subjects aged >/= 44 years using both statistical models. Comparisons with previous reports demonstrated a homogeneity in the decline in VA with age. On average, 0.3 logMAR are lost from middle age up to 88 years, presumably as a result of physiological ageing. In early ARM, the rate of age-specific decline in VA more than doubled and the prevalence of VA < 0.5 markedly increased. Conclusions: Visual acuity in healthy eyes declines with age from middle age onwards. The decrease in VA possibly accelerates in subjects aged > 70 years, although no significant evidence for this was found. An age-specific decline in VA is shown in eyes with early ARM. These results are important for the evaluation of age-specific treatment results.
机译：目的：本研究旨在分析两个年龄≥70岁的斯堪的纳维亚人群样本在正常衰老过程中视敏度（VA）的下降，并研究与年龄相关的黄斑病变早期的特定年龄的VA下降（臂）。方法：我们对来自芬兰奥卢（OU）（年龄70-82岁）和瑞典哥德堡（GG）（瑞典）（年龄70-82岁）的一个人群样本中与视力相关的VA数据进行了横截面分析82或88岁）。使用线性回归评估健康眼睛（OU，n = 119; GG，n = 40）和早期ARM（OU-ARM，n = 22; GG-ARM，n = 114）的VA随年龄的变化或逻辑回归。将结果与以前的报告进行了比较。结果：使用这两种统计模型，在年龄大于/ = 44岁的受试者中，健康人群的VA样本均随着VA年龄显着下降。与以前的报告比较表明，VA的下降随着年龄的增长是均匀的。平均而言，中年至88岁会损失0.3 logMAR，大概是由于生理老化造成的。在ARM早期，VA的年龄特异性下降率增加了一倍以上，VA ＜0.5的患病率明显增加。结论：从中年以后，健康眼睛的视力随年龄下降。 VA的降低可能在年龄大于70岁的受试者中加速，尽管没有发现明显的证据。早期ARM的眼睛显示出特定年龄的VA下降。这些结果对于评估特定年龄的治疗结果非常重要。

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