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首页> 外文期刊>Biofuels, bioproducts & biorefining: Biofpr >Low-cost medium for 1,3-propanediol production from crude glycerol byClostridium butyricum
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Low-cost medium for 1,3-propanediol production from crude glycerol byClostridium butyricum

机译:来自粗甘油的1,3-丙二醇生产的低成本培养基来自甘油的粗甘油肺霉素

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摘要

Bio-based 1,3-propanediol demand has increased in recent years; however, its production costs are still not competitive in some markets. In this study, Plackett-Burman designs were used to cost medium reduction and 1,3-propanediol production improvement withClostridium butyricum. A simple culture medium for 1,3-propanediol production from crude glycerol using the strainC. butyricumNCIMB 8082 was obtained by eliminating nine components of the usual culture medium. A 5 L fermentation using this simple culture medium was carried out in two steps. The final 1,3-propanediol concentration was 73.07 g.L-1, achieving a productivity of 3.7 g.L-1.h(-1)during the fed-batch step. The low-cost medium resulted in a 37% reduction in culture medium cost and a saving of 31% per kg for 1,3-propandiol produced in comparison with other non-complex media for 1,3-propanediol production from crude glycerol reported in the literature (c) 2020 Society of Chemical Industry and John Wiley & Sons, Ltd.
机译:基于生物的1,3-丙二醇需求近年来增加了; 然而,其生产成本仍然在某些市场中仍然不具有竞争力。 在这项研究中,Plackett-Burman设计用于降低中等减少和1,3-丙二醇的生产改善,用Clostridium诱捕。 一种简单的培养基,使用菌株从粗甘油从粗甘油产生1,3-丙二醇。 通过消除通常培养培养基的九个组分获得诱捕率。 使用该简单培养基的5L发酵分为两个步骤。 最终的1,3-丙二醇浓度为73.07g1-1,在进料批次步骤期间达到3.7g1-1.h(-1)的生产率。 低成本介质导致培养基成本降低了37%,与其他非复合培养基相比,培养基中成本降低了每公斤的31%,与其他非复合培养基为来自粗甘油的其他非复合培养基 文学(c)2020化学工业协会和约翰瓦里和儿子有限公司

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