An Alternative Method for Evaluating Stabilities of DNA Hairpin Structures

Zhang Hao; Ba Sai; Co Sarajane Co; Lee Jasmine Yiqin; Guo Juanjuan; Ye Ruijuan; Liang Zhaoxun; Huang Dejian; Li Tianhu

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An Alternative Method for Evaluating Stabilities of DNA Hairpin Structures

机译：一种评估DNA发夹结构稳定性的替代方法

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We have developed an alternative methodology for determining the stabilities of DNA hairpin structures based on a specially designed oligonucleotide template and the T4 DNA ligase. This method was systematically tested by evaluation of DNA hairpin stabilities when varying the loop size and the nature of the loop sequence.

机译：我们开发了一种替代方法，用于确定基于专门设计的寡核苷酸模板和T4 DNA连接酶的DNA发夹结构的稳定性。通过在改变环尺寸和环序列的性质时评估DNA发夹稳定性来系统地测试该方法。

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《Bulletin of the Chemical Society of Japan》 |2015年第9期|共3页
作者
Zhang Hao; Ba Sai; Co Sarajane Co; Lee Jasmine Yiqin; Guo Juanjuan; Ye Ruijuan; Liang Zhaoxun; Huang Dejian; Li Tianhu;
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作者单位

Nanyang Technol Univ Sch Phys &

Math Sci Div Chem &

Biol Chem Singapore 637371 Singapore;

Nanyang Technol Univ Sch Phys &

Math Sci Div Chem &

Biol Chem Singapore 637371 Singapore;

Nanyang Technol Univ Sch Phys &

Math Sci Div Chem &

Biol Chem Singapore 637371 Singapore;

Nanyang Technol Univ Sch Phys &

Math Sci Div Chem &

Biol Chem Singapore 637371 Singapore;

Natl Univ Singapore Dept Chem Singapore 117543 Singapore;

Nanyang Technol Univ Sch Biol Sci Div Struct Biol &

Biochem Singapore 637551 Singapore;

Nanyang Technol Univ Sch Biol Sci Div Struct Biol &

Biochem Singapore 637551 Singapore;

Natl Univ Singapore Dept Chem Singapore 117543 Singapore;

Nanyang Technol Univ Sch Phys &

Math Sci Div Chem &

Biol Chem Singapore 637371 Singapore;

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正文语种 eng
中图分类化学;
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1. An Alternative Method for Evaluating Stabilities of DNA Hairpin Structures [J] . Zhang Hao, Ba Sai, Co Sarajane Co, Bulletin of the Chemical Society of Japan . 2015,第9期

机译：一种评估DNA发夹结构稳定性的替代方法
2. STABILITY OF INTRASTRAND HAIRPIN STRUCTURES FORMED BY THE CAG/CTG CLASS OF DNA TRIPLET REPEATS ASSOCIATED WITH NEUROLOGICAL DISEASES [J] . Petruska J, Arnheim N, Goodman MF Nucleic Acids Research . 1996,第11期

机译：CAG / CTG类与神经疾病相关的DNA三连串重复形成的内部发夹结构的稳定性
3. Impact of alternative DNA structures on DNA damage, DNA repair, and genetic instability [J] . Guliang Wang, Karen M. Vasquez DNA repair . 2014,第Null期

机译：替代性DNA结构对DNA损伤，DNA修复和遗传不稳定的影响
4. New hairpin-structured DNA probes: alternatives to classical molecular beacons [C] . Achim Friedrich, Gregor Habl, Markus Sauer, Ultrasensitive and Single-Molecule Detection Technologies II; Progress in Biomedical Optics and Imaging; vol.8 no.21; Proceedings of SPIE-The International Society for Optical Engineering; vol.6444 . 2007

机译：新的发夹结构DNA探针：经典分子信标的替代品
5. Effects of DNA Binding on the Structure of Bleomycin Analogs and DNA Hairpins Examined by NMR Spectroscopy. [D] . Follett, Shelby E. 2017

机译：DNA结合对博来霉素类似物和NMR光谱检查的DNA发夹结构的影响。
6. Stability of intrastrand hairpin structures formed by the CAG/CTG class of DNA triplet repeats associated with neurological diseases. [O] . J Petruska, N Arnheim, M F Goodman 1996

机译：由CAG / CTG类DNA三联体重复序列形成的链内发夹结构的稳定性与神经系统疾病有关。
7. Stability of intrastrand hairpin structures formed by the CAG/CTG class of DNA triplet repeats associated with neurological diseases. [O] . Petruska, J, Arnheim, N, Goodman, M F 1996

机译：由CAG / CTG类DNA三联体重复序列形成的链内发夹结构的稳定性与神经系统疾病有关。
8. Repair, Evaluation, Maintenance, and Rehabilitation Research Program: Methods of Evaluating the Stability and Safety of Gravity Earth Retaining Structures Founded on Rock. [R] . Eberling, R. M., Clough, G. W., Duncan, J. M., 1992

机译：修复，评估，维护和修复研究计划：评估岩石上建立的重力土挡土结构的稳定性和安全性的方法。

An Alternative Method for Evaluating Stabilities of DNA Hairpin Structures

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