Dimerization of 1-methyl-substituted pyrrolo[1,2-a]pyrazines during acetylation

V. I. Terenin; M. A. Butkevich; A. S. Ivanov

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Dimerization of 1-methyl-substituted pyrrolo[1,2-a]pyrazines during acetylation

机译：乙酰化期间1-甲基取代的吡咯并[1,2-a]吡嗪的二聚化

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The pyrrolo[1,2-a]pyrazine system is relatively stable against the action of weak electrophiles, as shown by the fact that 6-acetylpyrrolo[1,2-a]pyrazine is formed with a yield of only 16% when unsubstituted pyrrolo[1,2-a]pyrazine is boiled with an excess of acetic anhydride for 24 h [1].

机译：吡咯并[1,2-a]吡嗪系统对弱电子手术的作用相对稳定，如图6-乙酰吡咯烷[1,2-a]吡嗪所示，当未取代的吡咯时的产率仅为16％ [1,2-A]吡嗪用过量的乙酸酐煮沸24小时[1]。

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来源
《Chemistry of heterocyclic compounds》 |2006年第8期|共3页
作者
V. I. Terenin; M. A. Butkevich; A. S. Ivanov;
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作者单位

M. V. Lomonosov Moscow State University Moscow 119992 Russia;

M. V. Lomonosov Moscow State University Moscow 119992 Russia;

M. V. Lomonosov Moscow State University Moscow 119992 Russia;

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原文格式 PDF
正文语种 eng
中图分类杂环化合物;
关键词
pyrrolo1; 2-apyrazines; acylation; dimerization;

机译：Pyrrolo [1;2-a]吡嗪;酰化;二聚化;

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1. Dimerization of 1-methyl-substituted pyrrolo[1,2-a]pyrazines during acetylation [J] . V. I. Terenin, M. A. Butkevich, A. S. Ivanov Chemistry of heterocyclic compounds . 2006,第8期

机译：乙酰化期间1-甲基取代的吡咯并[1,2-a]吡嗪的二聚化
2. Synthesis of new 4-(2-(alkylamino) ethylthio)pyrrolo(1,2-a)quinoxaline and 5-(2-(alkylamino) ethylthio)pyrrolo(1,2-a)thieno(3,2-e)pyrazine derivatives, as potential bacterial multidrug resistance pump inhibitors. [J] . Vidaillac C, Guillon J, Moreau S, Journal of enzyme inhibition and medicinal chemistry. . 2007,第5期

机译：合成新的4-（2-（烷基氨基）乙硫基）吡咯并（1,2-a）喹喔啉和5-（2-（烷基氨基）乙硫基）吡咯并（1,2-a）噻吩并（3,2-e）吡嗪衍生物，作为潜在的细菌多药耐药泵抑制剂。
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5. Synthetic studies toward aziridinomitosenes and 9-oxo-pyrrolo[1,2-a]indole mitosanes related to the mitomycin and FR heterocycles. [D] . Wiedner, Susan D. 2009

机译：对与丝裂霉素和FR杂环化合物有关的叠氮基丝氨酸和9-氧代-吡咯并[1,2-a]吲哚有丝分裂的合成研究。
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机译：新吡咯（1,2-A）喹喔啉，双吡咯（1,2-A）喹喔啉，双吡啶（3,2-e）吡咯醇（1,2-A）吡嗪和吡嗪（1,2-吡咯醇（1）的合成，抗疟活动，2-a）Thieno（3,2-e）吡嗪

Dimerization of 1-methyl-substituted pyrrolo[1,2-a]pyrazines during acetylation

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