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The Nottingham Fatigue after Stroke (NotFAST) study: factors associated with severity of fatigue in stroke patients without depression

机译:中风(NOTFAST)研究后的诺丁汉疲劳:与卒中患者疲劳严重程度相关的因素,没有抑郁症

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Objective: To identify factors associated with post-stroke fatigue in a sample of stroke survivors without depression. Design: Cross-sectional cohort study. Setting: Recruitment was from four stroke units in the UK. Subjects: Participants were assessed within four to six weeks of first stroke; those with high levels of depressive symptoms (score ?7 Brief Assessment Schedule Depression Cards) were excluded. Main measures: Participants were assessed after stroke on the Fatigue Severity Scale of the Fatigue Assessment Inventory, the Rivermead Mobility Index, Nottingham Extended Activities of Daily Living scale, Beck Anxiety Index, Sleep Hygiene Index, 6m walk test, and measures of cognitive ability. Results: Of the 371 participants recruited, 103 were excluded and 268 were assessed. Of the latter, the mean age was 67.7 years (SD 13.5) and 168 (63%) were men. The National Institutes of Health Stroke Scale mean score was 4.96 (SD 4.12). Post-stroke fatigue was reported by 115 (43%) of participants, with 71 (62%) reporting this to be a new symptom since their stroke. Multivariate analysis using the Fatigue Severity Scale as the outcome variable found pre-stroke fatigue, having a spouse/partner, lower Rivermead Mobility Index score, and higher scores on both the Brief Assessment Schedule Depression Cards and Beck Anxiety Index were independently associated with post-stroke fatigue, accounting for approximately 47% of the variance in Fatigue Severity Scale scores. Conclusions: Pre-stroke fatigue, lower mood, and poorer mobility were associated with post-stroke fatigue.
机译:目的:鉴定与卒中幸存者样品中卒中后疲劳相关的因素,没有抑郁。设计:横截面队列研究。环境:招聘来自英国的四个笔划。主题:参与者在第一次中风的四到六周内进行评估;那些抑郁症状患者(分数?7简要评估进度抑郁卡)被排除在外。主要措施:参与者在中风上进行疲劳评估库存疲劳严重程度,Rivermead移动性指数,诺丁汉延长活动的日常生本规例,贝克焦虑指数,睡眠卫生指数,6M步行试验以及认知能力的措施。结果:招募的371名参与者中,排除了103名,评估了268名。后者,平均年龄为67.7岁(SD 13.5)和168名(63%)是男性。国家卫生学院卒中规模平均得分为4.96(SD 4.12)。 115名(43%)的参与者报告了卒中后疲劳,71(62%)报告这是自中风以来的新症状。使用疲劳严重程度的多变量分析作为结果变量发现前卒中前疲劳,具有配偶/伴侣,降低rivermead移动性指数评分,以及短暂评估进度抑郁卡和Beck焦虑指数的更高分数与后期独立相关中风疲劳,占疲劳严重程度评分的差异约47%。结论:预备疲劳,情绪降低,迁移率较差,与中风后疲劳有关。

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