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首页> 外文期刊>Clinical EEG and neuroscience: official journal of the EEG and Clinical Neuroscience Society (ENCS) >The Significance of Interictal Spike Frequency in Temporal Lobe Epilepsy
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The Significance of Interictal Spike Frequency in Temporal Lobe Epilepsy

机译：颞叶癫痫中嵌段穗频率的重要性

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Purpose . In this study, the frequency of interictal epileptiform discharges (IEDs) in patients with drug-resistant temporal lobe epilepsy (TLE) was measured to determine its correlation with epilepsy duration, seizure frequency, brain magnetic resonance imaging (MRI) findings, and recent occurrence of focal to bilateral tonic clonic seizures (FBTCS). Methods . Our study was performed on TLE patients, who admitted to epilepsy monitoring unit of Loghman-Hakim hospital, Tehran, from 2016 to 2018. The patients’ IEDs frequency were measured from their scalp EEG recording during no–rapid eye movement (NREM) sleep. The IEDs frequency was classified into 3 groups of rare, occasional, and frequent. Results . A total of 142 patients, with the mean age of 33.95 ± 12.73 years, were included in the study. The patients’ mean epilepsy duration was 17.27 ± 12.19 years and the mean seizure frequency was 10.56 ± 12.95 attacks per month. The mean IEDs frequency was 123.48 ± 513.01 per hour. Thirty-five (24.6%) patients had history of FBTCS in the past year. Our findings revealed no significant association between IEDs frequency with epilepsy duration ( P = .22), the recent occurrence of FBTCS ( P = .42), and the type of MRI abnormalities ( P = .66). There was only a weak positive correlation between seizure frequency and interictal spike density ( r = 0.2, P = .007). Conclusions . In patients with TLE, standard EEG recording may not be a reliable method to predict the probability of occurring future seizures.
机译：目的 。在本研究中，测量耐药时间叶癫痫（TLE）患者的嵌入癫痫型排放（IED）的频率，以确定其与癫痫持续时间，癫痫发作频率，脑磁共振成像（MRI）结果的相关性和最近的发生焦点对双侧补液克隆癫痫发作（FBTCS）。方法 。我们的研究表演，从2016年到2018年录取了德黑兰Loghman-Hakim医院的癫痫监测单位的Tleepsy监测单位。患者的IED频率是从他们的头皮EEG记录中测量的，在没有快速的眼球运动（NREM）睡眠期间。 IED频率被分为3组罕见，偶尔和频繁。结果 。共有142名患者，平均年龄为33.95±12.73岁，包括在研究中。患者的平均癫痫持续时间为17.27±12.19岁，平均癫痫发作频率为每月10.56±12.95次攻击。平均IED频率为每小时123.48±513.01。 35名（24.6％）患者在过去一年中有FBTC的历史。我们的研究结果揭示了IED频率与癫痫持续时间（p = .22）之间的显着关联，最近发生的FBTC（P = .42），以及MRI异常的类型（P = .66）。癫痫发作频率和闭式尖峰密度之间仅存在弱的正相关（r = 0.2，p = .007）。结论。在TLE患者中，标准EEG录制可能不是可靠的方法来预测发生未来癫痫发作的可能性。

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