The Study of Pain in Rats and Mice

Larson Christina M.; Wilcox George L.; Fairbanks Carolyn A.

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The Study of Pain in Rats and Mice

机译：大鼠疼痛的研究

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Pain is a clinical syndrome arising from a variety of etiologies in a heterogeneous population, which makes successfully treating the individual patient difficult. Organizations and governments recognize the need for tailored and specific therapies, which drives pain research. This review summarizes the different types of pain assessments currently being used and the various rodent models that have been developed to recapitulate the human pain condition.

机译：疼痛是一种临床综合征，由异质群体中的各种病因产生，这使得成功地治疗个体患者困难。组织和政府认识到需要量身定制和特定的疗法，推动疼痛研究。本综述总结了目前正在使用的不同类型的疼痛评估以及开发的各种啮齿动物模型，以重新承载人类疼痛状况。

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《Comparative Medicine》 |2019年第6期|共16页
作者
Larson Christina M.; Wilcox George L.; Fairbanks Carolyn A.;
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作者单位

Univ Minnesota Coll Vet Med Comparat &

Mol Biosci St Paul MN 55108 USA;

Univ Minnesota Sch Med Dept Neurosci Minneapolis MN 55455 USA;

Univ Minnesota Sch Med Dept Neurosci Minneapolis MN 55455 USA;

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原文格式 PDF
正文语种 eng
中图分类畜牧、动物医学、狩猎、蚕、蜂;
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1. The Ehrlich Tumor Induces Pain-Like Behavior in Mices A Novel Model of Cancer Pain for Pathophysiological Studies and Pharmacological Screening [J] . Cassia Calixto-Campos, Ana C. Zarpelon, Mab Correa, BioMed research international . 2013,第Pta19期

机译：Ehrlich肿瘤会诱发类似痛的行为，一种用于病理生理学研究和药理学筛选的新型癌症疼痛模型
2. Analgesic Effect of Moxibustion with Different Temperature on Inflammatory and Neuropathic Pain Mice: A Comparative Study [J] . Zhou Wei, Lei Ruxue, Zuo Chuanyi, Evidence-based complementary and alternative medicine: eCAM . 2017,第9期

机译：不同温度对炎症和神经性疼痛小鼠不同温度的镇痛作用：比较研究
3. ARA290, a peptide derived from the tertiary structure of erythropoietin, produces long-term relief of neuropathic pain: an experimental study in rats and beta-common receptor knockout mice. [J] . Swartjes M, Morariu A, Niesters M, Anesthesiology . 2011,第5期

机译：ARA290是一种来自促红细胞生成素三级结构的肽，可长期缓解神经性疼痛：这是一项在大鼠和β-共受体敲除小鼠中进行的实验研究。
4. Bio-MEMS based sensor for acute and chronic pain management: An online measurement strategy for using biomedicai MEMS sensor in the assessment of pain intensity and study of inflammation [C] . Sathiyabama G., Krishnan S. Sankara, Saravanan D., Second IEEE National Conference On Emerging Trends In New amp; Renewable Energy Sources amp; Energy Management . 2014

机译：用于急性和慢性疼痛管理的基于生物MEMS的传感器：使用生物医学MEMS传感器评估疼痛强度和研究炎症的在线测量策略
5. Two Narratives on Chronic Pain Management: A Qualitative Study on the Lived Experiences of Two Individuals Living with Chronic Pain [D] . Jiang, Zhixin. 2018

机译：慢性疼痛管理的两种叙述：对两个慢性疼痛患者的生活经历的定性研究
6. Transgenic Mice Expressing MCP-1 by the Urothelium Demonstrate Bladder Hypersensitivity Pelvic Pain and Voiding Dysfunction: A Multidisciplinary Approach to the Study of Chronic Pelvic Pain Research Network Animal Model Study [O] . Suming Xu, Xu Wang, Yaoqin Wang, -1

机译：尿路上皮表达MCP-1的转基因小鼠表现出膀胱超敏性盆腔痛和呕吐功能障碍：慢性盆腔痛研究网络动物模型研究的多学科方法
7. Transgenic Mice Expressing MCP-1 by the Urothelium Demonstrate Bladder Hypersensitivity, Pelvic Pain and Voiding Dysfunction: A Multidisciplinary Approach to the Study of Chronic Pelvic Pain Research Network Animal Model Study. [O] . Suming Xu, Xu Wang, Yaoqin Wang, 2016

机译：通过尿路上皮表达mCp-1的转基因小鼠表现出膀胱过敏，骨盆疼痛和排尿功能障碍：慢性盆腔疼痛研究网络动物模型研究的多学科方法。
8. NTP Technical Report on the Toxicology Studies of Indole-3-Carbinol (CAS NO. 700-06-1) in F344/N Rats and B6C3F1/N Mice and Toxicology and Cardcinogenesis Studies of Indole-3-Carbinol in Harlan Sprague Dawley Rats and B6C3F1/N Mice (Gavage Studies). [R] . 2017

机译：NTp技术报告吲哚-3-甲醇（Cas NO.700-06-1）在F344 / N大鼠和B6C3F1 / N小鼠中的毒理学研究和Harlan sprague Dawley大鼠中吲哚-3-甲醇的毒理学和致癌作用研究B6C3F1 / N小鼠（灌胃研究）。

The Study of Pain in Rats and Mice

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