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首页> 外文期刊>Clinical and experimental obstetrics and gynecology >Associations of pre-pregnancy obesity with adverse pregnancy outcomes and the optimal gestational weight gain in Japanese women
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Associations of pre-pregnancy obesity with adverse pregnancy outcomes and the optimal gestational weight gain in Japanese women

机译：妊娠前腹期性腹期性腹期性腹期性和日本女性的最佳妊娠重量增益

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Objectives: The authors determined associations of maternal pre-pregnancy obesity with adverse pregnancy outcomes and evaluated how gestational weight gain affects risks for such outcomes in Japanese obese pregnant women. Materials and Methods: Among women who delivered at the Perinatal Center for Maternity and Neonatal, Yokohama City University Medical Center, between January 2001 and December 2012, the authors ascertained adverse pregnancy outcome incidences in 207 pre-pregnancy obese (body mass index [BMI] = 30 kg/m(2), obese group), 661 pre-pregnancy overweight (BMI = 25-29.9 kg/m2, overweight group), and 6,801 pre-pregnancy normal weight (BMI = 18.5-24.9 kg/m(2), normal group) women. Subjects were stratified by weekly weight gain during the second/third trimesters to investigate associations between gestational weight gain and adverse pregnancy outcomes. Optimal weight gain for obese pregnant women was also examined. Results: In the obese and overweight groups, incidences of pregnancy induced hypertension (PIH), gestational diabetes mellitus (GDM), large for gestational age (LGA), preterm birth, preterm prelabor rupture of membranes (PPROM), and spontaneous preterm birth were significantly higher than in the normal group. Incidences of adverse pregnancy outcomes were apparently higher in the obese than in the overweight group. In the latter, the incidence of large for gestational age was significantly higher in women with weight gains of 0.5kg/week, whereas no difference in pregnancy outcomes was observed in the obese group regardless of gestational weight gain. Conclusion: In obese women, incidences of adverse pregnancy outcomes were higher, and pregnancy outcomes were difficult to improve with gestational weight control. Thus, it is important to reach an optimal weight before pregnancy.
机译：目标：作者确定了孕产妇前孕期肥胖的关联与不良妊娠结果，并评估了妊娠重量增益如何影响日本肥胖孕妇的这种结果的风险。材料和方法：在2001年1月至2012年12月间在横滨市大学医疗中心围产产妇和新生儿的围产期和新生儿妇女，作者在207年妊娠肥胖前的不利妊娠结局发生了不利的怀孕成果（体重指数[BMI] = 30kg / m（2），肥胖组），661孕前超重（BMI = 25-29.9kg / m2，超重群），6,801次妊娠正常重量（BMI = 18.5-24.9 kg / m（2 ），正常组）女性。在第二个/第三三个月的时间重量增益在第二/第三个三孢子期间进行分层，以研究妊娠重量增益和不良妊娠结果之间的关联。还检查了肥胖孕妇的最佳体重增加。结果：在肥胖和超重群体中，怀孕诱导高血压（PIH），妊娠期糖尿病（GDM），妊娠期大（LGA），早产，早产的膜（PPROM）的破裂，以及自发早产显着高于正常组。不良妊娠结果的发病率在肥胖中显然比超重群体更高。在后者中，妊娠期大的孕龄的发生率为0.5kg /周的妇女显着高，而无论妊娠重量增益如何，肥胖组在肥胖组中观察到妊娠结果的差异。结论：在肥胖女性中，妊娠期结果的发病率较高，妊娠期妊娠期妊娠结果难以改善。因此，重要的是在怀孕前达到最佳重量。

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