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Academic achievement of adolescents with asthma or atopic disease

机译：哮喘或特应性疾病的青少年学业成就

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Summary Background Over a fifth of children and adolescents suffer with asthma or atopic disease. It is unclear whether asthma impacts academic performance in children and adolescents, and little is known about the association of eczema, food allergy or hayfever and academic performance. Objective To examine whether asthma, eczema, food allergy or hayfever impacts on adolescent academic performance and to assess the role of unmeasured confounding. Methods This study used the Childhood and Adolescent Twin Study of Sweden cohort born 1992‐1998. At age 9‐12?years, parents reported on their child's ever or current asthma, eczema, food allergy and hayfever status (n?=?10?963). At age 15, linked national patient and medication register information was used to create current and ever asthma definitions including severe and uncontrolled asthma for the same children. Academic outcomes in Grade 9 (age 15‐16?years) included: eligibility for high school (Grades 10‐12), and total mark of the best 16 subject units, retrieved from the Grade 9 academic register. Whole cohort analyses adjusted for known covariates were performed, and co‐twin control analyses to assess unmeasured confounders. Results There were no associations found for asthma or food allergy at 9‐12?years and academic outcomes in adolescence. In addition, at age 15, there were no statistically significant associations with current, ever, severe or uncontrolled asthma and academic outcomes. Eczema and hayfever at age 9‐12?years were found to be positively associated with academic outcomes; however, co‐twin control analyses did not support these findings, suggesting the main analyses may be subject to unmeasured confounding. Conclusion and clinical relevance Having asthma or an atopic disease during childhood or adolescence does not negatively impact on academic performance. This information can be used by clinicians when talking with children and parents about the implications of living with asthma or atopic disease.
机译：摘要背景五分之一儿童和青少年患有哮喘或特应性疾病。目前尚不清楚哮喘是否会影响儿童和青少年的学术表现，并且关于湿疹，食物过敏或喜福型和学术表现的关联知之甚少。目的探讨哮喘，湿疹，食物过敏或枯萎对青少年学业绩效的影响，并评估未测量混淆的作用。方法采用1992-1998的瑞典群岛童年和青少年双胞胎研究。在9-12岁时？几年，父母报道他们的孩子有史以来或目前的哮喘，湿疹，食物过敏和Hayfever身份（n？=？10？963）。 15年龄在15岁时，联系的国家患者和药物注册信息被用来创造目前的哮喘定义，包括同一儿童严重和不受控制的哮喘。 9年级（15-16岁）的学术结果包括：高中（10-12级）的资格，以及从9年级学术登记册中检索的最佳16个主题单位的总标记。进行了针对已知协变量调整的整个队列分析，并进行了共同控制分析，以评估未测量的混淆。结果在9-12岁的时候没有发现哮喘或食物过敏的关联，青春期的年龄和学术结果。此外，在15岁时，没有统计学上的重要组织与目前，永远，严重或不受控制的哮喘和学术结果。 9-12岁的湿疹和枯草惠韦彼得多年份被发现与学术成果积极相关;然而，共同对照分析并不支持这些发现，表明主要分析可能受到未测量的混杂性。结论和患儿童或青春期的哮喘或特应性疾病的临床相关性对学术表现产生负面影响。临床医生可以在与儿童和父母与哮喘或特应性疾病的影响谈话时，临床医生可以使用这些信息。

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