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Hand eczema and occupational contact allergies in healthcare workers with a focus on rubber additives

机译:手中湿疹和职业接触过敏在医疗保健工作者中,专注于橡胶添加剂

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Background Hand eczema (HE) in healthcare workers (HCWs) is common. Besides wet work, healthcare work also implies exposure to contact allergens. Objectives To assess HE and contact allergy related to occupational exposures in HCWs. Methods In a cross‐sectional study, 311 HCWs with HE within the preceding 12?months and a control group of 114 HCWs without HE were investigated with the baseline series and a special patch test series based on substances found in the gloves, soaps, alcoholic hand disinfectants and hand creams provided at the hospitals. Results Contact allergy to rubber additives was significantly more common in HCWs with HE (6%) than in HCWs without HE (1%, P ?=?.02). The corresponding percentages for fragrances were 11% and 3%, respectively ( P ?=?.004). Occupational HE was found in 193 of 311 (62%) HCWs. Of these, 22 of 193 (11%) had occupational allergic contact dermatitis, including 17 with glove‐related rubber contact allergy. Contact allergy to diphenylguanidine was as common as contact allergy to thiurams. Occupational contact allergy to rubber additives was significantly associated with sick‐leave related to HE. Conclusion Contact allergy to rubber additives in medical gloves is the most common cause of occupational allergic contact dermatitis in HCWs. Aimed patch testing with relevant rubber additives is mandatory when HE in HCWs is investigated.
机译:背景手湿疹(他)在医疗保健工人(HCW)是常见的。除了湿法工作外,医疗工作还意味着接触过敏原。目标评估他和与HCW中职业暴露相关的接触过敏。横断面研究中的方法,在前面的12个月中311个HCWS,其中11个月和114个HCW的对照组,没有他的基础系列和特殊的贴片测试系列,基于手套,肥皂,酗酒的物质在医院提供的手用消毒剂和手奶油。结果与橡胶添加剂的接触过敏与橡胶添加剂在HCW中具有比没有他(1%,P?= 02)的HCW(6%)更常见。相应的香料百分比分别为11%和3%(p?= 004)。职业他在311(62%)HCW中被发现。其中,193例(11%)的22例(11%)具有职业过敏性接触皮炎,其中17种带有与手套相关的橡胶接触过敏。对二苯基胍的接触过敏与Thiurams的接触过敏一样常见。橡胶添加剂的职业接触过敏与与他有关的病假显着相关。结论医疗手套橡胶添加剂的接触过敏是HCWS中职业过敏性接触皮炎最常见的原因。当研究他的HCWS时,旨在使用相关橡胶添加剂的贴补测试是强制性的。

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