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首页> 外文期刊>Contact dermatitis >Patch testing with alkyl glucosides: Concomitant reactions are common but not ubiquitous
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Patch testing with alkyl glucosides: Concomitant reactions are common but not ubiquitous

机译：用烷基葡糖苷的贴剂测试：伴随的反应是常见的，但不是普遍存在的

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Background Alkyl glucosides contitute a family of mild surfactants that are increasingly being used in a wide range of cosmetics and household products. Contact allergy to alkyl glucosides may be more frequent than previously suspected, especially in atopic patients. Objectives To investigate the frequency of contact allergy to alkyl glucosides, and to identify concomitant reactivity. Method We retrospectively reviewed all cases of suspected allergic contact dermatitis (ACD) in which patients were patch tested with either a cosmetic series that includes five alkyl glucosides (decyl glucoside, lauryl glucoside, coco glucoside, cetearyl glucoside, and caprylyl/capryl glucoside) or a specific alkyl glucoside series from November 2013 to April 2017 in two UK centres. Results A total of 5775 patients were patch tested across the two centres. Twenty‐nine (1.04%) of the 2796 patients tested with the cosmetic/alkyl glucoside series had a positive patch test reaction to at least one of the alkyl glucosides. Twenty‐three (79.3%) patients were sensitized to multiple alkyl glucosides; 21 patients (72.4%) were female. The mean age was 43.5 years. Twelve patients (41.4%) had a background of atopic dermatitis. Conclusions The prevalence of alkyl glucoside‐induced ACD is relatively high, and there are frequent concomitant reactions between different alkyl glucosides. We recommend the inclusion of alkyl glucosides in all cosmetic series.
机译：背景技术烷基葡糖苷是一种温和的表面活性剂，越来越多地用于各种化妆品和家用产品。对烷基葡糖苷的接触过敏可能比以前怀疑，特别是在特应患者中更频繁。目的探讨接触过敏的频率对烷基葡糖苷，并鉴定伴随的反应性。方法回顾性地审查了所有疑似过敏性接触性皮炎（ACD）的病例，其中患者用包含五种烷基葡糖苷（癸基葡糖苷，月桂糖苷，可可葡糖苷，所述葡糖葡萄糖苷，所述葡糖葡萄糖苷和铜/甲酰葡糖苷）或2013年11月至2017年4月在两个英国中心的特定烷基葡糖苷系列。结果共有5775名患者在两中心测试贴片。用化妆品/烷基葡糖苷系列测试的2796名患者的2796名（1.04％）对至少一种烷基葡糖苷具有正贴剂测试反应。二十三（79.3％）患者对多种烷基葡糖苷敏化; 21例患者（72.4％）是女性。平均年龄为43.5岁。 12名患者（41.4％）具有特应性皮炎的背景。结论烷基葡糖苷诱导的ACD的患病率相对较高，并且在不同烷基葡糖苷之间经常存在伴随反应。我们建议在所有化妆品系列中含有烷基葡糖苷。

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