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首页> 外文期刊>Critical care medicine >The Fragility and Reliability of Conclusions of Anesthesia and Critical Care Randomized Trials With Statistically Significant Findings: A Systematic Review
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The Fragility and Reliability of Conclusions of Anesthesia and Critical Care Randomized Trials With Statistically Significant Findings: A Systematic Review

机译:麻醉和关键护理随机试验结论的脆弱性和可靠性,具有统计学意义:系统审查

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摘要

Objectives: The Fragility Index, which represents the number of patients responsible for a statistically significant finding, has been suggested as an aid for interpreting the robustness of results from clinical trials. A small Fragility Index indicates that the statistical significance of a trial depends on only a few events. Our objectives were to calculate the Fragility Index of statistically significant results from randomized controlled trials of anesthesia and critical care interventions and to determine the frequency of distorted presentation of results or "spin".
机译:目的:代表负责统计上显着发现的患者数量的脆弱性指数,提出了解释临床试验结果的稳健性的援助。 一个小脆弱索引表明试验的统计显着性取决于几个事件。 我们的目标是计算麻醉和关键护理干预的随机对照试验的统计上显着结果的脆弱指数,并确定扭曲结果呈现的频率或“旋转”。

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