Evidence of antiplatelet aggregation effects from the consumption of tomato products, according to EFSA health claim requirements

Camara Montana; Fernandez-Ruiz Virginia; Sanchez-Mata Maria-Cortes; Diaz Laura; Kardinaal Alwine; van Lieshout Machteld

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Evidence of antiplatelet aggregation effects from the consumption of tomato products, according to EFSA health claim requirements

机译：根据EFSA健康索赔要求，番茄产品消耗的抗血小板聚集效应的证据

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The beneficial effect of fresh tomatoes or processed tomato products on platelet aggregation depends on the presence of bioactive compounds in these products, in sufficient quantities, to produce a relevant physiological effect, when consumed as part of a normal diet. This work is focused on reviewing the development on tomato products bioactive compounds, particularly with reference to its potential biological activity with beneficial effect on the prevention of platelet aggregation. The most relevant studies found show that all bioactive compounds found in Water-soluble tomato concentrate are in tomato fruit and other tomato products, and there is enough evidence of their beneficial effects. According to the European Food Safety Authority requirements, further intervention studies (human clinical trials) using valid markers should be performed in order to demonstrate the beneficial effects of tomato products as consumer products (paste, puree, sauce or juice) on platelet aggregation. Our PubMed review results support the development of promising nutritional strategies involving tomatoes and tomato products to tackle cardiovascular disease as antiplatelet aggregation.

机译：新鲜西红柿或加工番茄产品对血小板聚集的有益效果取决于这些产品中的生物活性化合物的存在，以足够的量，当作为正常饮食的一部分消耗时产生相关的生理效果。这项工作旨在审查番茄产品生物活性化合物的开发，特别是参考其潜在的生物活性，对预防血小板聚集的有益作用。发现最相关的研究表明，在水溶性番茄浓缩物中发现的所有生物活性化合物都是番茄果和其他番茄产品，并且有足够的证据证明了他们的有益效果。根据欧洲食品安全管理局要求，应进行进一步的干预研究（人类临床试验）使用有效标记进行番茄产品作为消费品（粘贴，泥，酱汁或果汁）对血小板聚集的有益效果。我们的PubMed检讨结果支持开发涉及西红柿和番茄产品的有前途的营养策略，以解决心血管疾病作为抗血管疾病。

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来源
《Critical Reviews in Food Science and Nutrition》 |2020年第12期|共8页
作者
Camara Montana; Fernandez-Ruiz Virginia; Sanchez-Mata Maria-Cortes; Diaz Laura; Kardinaal Alwine; van Lieshout Machteld;
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作者单位

Univ Complutense Madrid Fac Pharm Dept Nutr &

Food Sci Madrid Spain;

Univ Complutense Madrid Fac Pharm Dept Nutr &

Food Sci Madrid Spain;

Univ Complutense Madrid Fac Pharm Dept Nutr &

Food Sci Madrid Spain;

Univ Complutense Madrid Fac Pharm Dept Nutr &

Food Sci Madrid Spain;

NIZO Food Res BV Ede Netherlands;

Foodwise Pro BV Driebergen Netherlands;

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原文格式 PDF
正文语种 eng
中图分类食品营养学;
关键词
tomato; health claims; platelet and antiplatelet;

机译：番茄;健康索赔;血小板和抗血小板;

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专利

1. Evidence of antiplatelet aggregation effects from the consumption of tomato products, according to EFSA health claim requirements [J] . Camara Montana, Fernandez-Ruiz Virginia, Sanchez-Mata Maria-Cortes, Critical Reviews in Food Science and Nutrition . 2020,第9a12期

机译：根据EFSA健康索赔要求，番茄产品消耗的抗血小板聚集效应的证据
2. Outcome of a public consultation on the Draft Opinion of the EFSA Panel on Dietetic Products, Nutrition, and Allergies (NDA) on a guidance on the scientific requirements for health claims related to antioxidants, oxidative damage and cardiovascular health [J] . EFSA supporting publications . 2011,第12期

机译：关于EFSA营养产品，营养和过敏委员会（NDA）意见草案的公众咨询结果，该草案涉及抗氧化剂，氧化损伤和心血管健康相关健康要求的科学要求指南
3. Outcome of a public consultation on the Draft Opinion of the EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA) on a draft guidance on the scientific requirements for health claims related to appetite ratings, weight management, and blood glucose concentrations [J] . EFSA supporting publications . 2012,第3期

机译：关于EFSA营养产品，过敏和过敏食品专家组（NDA）意见草案的公众咨询结果，该意见草案涉及与食欲分级，体重管理和血糖浓度有关的健康要求的科学要求指南草案
4. Dietary Supplements and Herbal Medicinal Products - for a Clear Differentiation. Statement of the Society for Phytotherapy (GPT) to the "Article 13 Health Claim List" of the EFSA [C] . Frauke Gaedcke, Bernd Eberwein, Olaf Felber, Symposium on Risk Assessment of Phytochemicals in Food: Novel Approaches . 2010

机译：膳食补充剂和草药产品 - 用于清晰的分化。植物治疗协会（GPT）对EFSA的“第13条健康索赔名单”的声明
5. Effects of the consumption of fresh and processed tomato products on blood and tissue lycopene concentrations. [D] . Allen, Charlotte Moxley. 2000

机译：食用新鲜和加工番茄制品对血液和组织番茄红素浓度的影响。
6. Antiplatelet protocol: Effects of ingesting a tomato pomace extract on human platelet aggregation [O] . Aníbal Concha-Meyer, Eduardo Fuentes, Iván Palomo 2019

机译：抗血小板方案：摄取番茄渣提取物对人血小板聚集的影响
7. EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA); Scientific Opinion on the substantiation of health claims related to: dairy products (ID 1140, 1141, 1191), raw or processed food products of animal origin, plus bread and panification products (ID 1193, 1194), herbal yeast plasmolysate (ID 1815, 1816), apple polyphenols (ID 2713), rye flour (ID 1266), tomato juice (ID 1202), whey protein and alphalactalbumin (ID 424, 430, 432, 725, 1433) and “brocco shoots”, “broccoli sprout powder” and “Brassica oleracea var. italica (broccoli)” (ID 1362, 1481, 2844, 2845), honey (ID 1159, 1160, 1318, 4678, 4679), and Cucurbita pepo L. (pumpkin) seed and seed extracts (ID 2029, 2365) pursuant to Article 13(1) of Regulation (EC) No 1924/2006 [O] . Tetens Inge 2011

机译：EFsa饮食产品，营养和过敏专家组（NDa）;关于健康声明的证据的科学意见：乳制品（ID 1140,1141,1191），动物源的原料或加工食品，以及面包和panification产品（ID 1193,1194），草药酵母plasmolysate（ID 1815， 1816），苹果多酚（ID 2713），黑麦粉（ID 1266），番茄汁（ID 1202），乳清蛋白和α-乳清蛋白（ID 424,430,432,725,1433）和“brocco shoots”，“西兰花芽粉” “和”Brassica oleracea var。 italica（西兰花）“（ID 1362,1481,2844,2845），蜂蜜（ID 1159,1160,1318,4678,4679）和南瓜子（种子）和种子提取物（ID 2029,2365）依据第（EC）1924/2006号条例第13（1）条

Evidence of antiplatelet aggregation effects from the consumption of tomato products, according to EFSA health claim requirements

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