Cortical developmental death: selected to survive or fated to die

Causeret Frederic; Coppola Eva; Pierani Alessandra

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Cortical developmental death: selected to survive or fated to die

机译：皮质发育死亡：选择生存或命中死亡

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The mature cerebral cortex only contains a fraction of the cells that are generated during embryonic development. Indeed some neuronal populations are produced in excess and later subjected to partial elimination whereas others are almost completely removed during the first two postnatal weeks in mice. Although the identity of cells that disappear, the time course and mechanisms of their death are becoming reasonably well established, the meaning of producing supernumerary cells still remains elusive. In this review, we focus on recent data that shed a new light on the mechanisms involved in adjusting cell numbers and discuss the significance of refinement versus complete elimination of cell populations in the developing cortex.

机译：成熟的脑皮质仅含有在胚胎发育期间产生的细胞的一部分。实际上，一些神经元群体以过量产生，后来经受部分消除，而其他神经元群体在小鼠的前两个后几周内几乎完全除去。尽管消失的细胞的身份，但其死亡的时间和机制正在相当得很好，但制备占星级细胞的意义仍然难以实现。在这篇综述中，我们专注于最近的数据揭示了在调整细胞数的机制上揭示了新的光线，并讨论了改进的重要性与开发皮质中的细胞群体完全消除细胞群体。

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来源
《Current Opinion in Neurobiology》 |2018年第2018期|共8页
作者
Causeret Frederic; Coppola Eva; Pierani Alessandra;
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作者单位

Univ Paris 05 Ctr Psychiat &

Neurosci INSERM UMR 894 Sorbonne Paris Cite Paris France;

Univ Paris 05 Ctr Psychiat &

Neurosci INSERM UMR 894 Sorbonne Paris Cite Paris France;

Univ Paris 05 Ctr Psychiat &

Neurosci INSERM UMR 894 Sorbonne Paris Cite Paris France;

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正文语种 eng
中图分类神经病学;
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1. Cortical developmental death: selected to survive or fated to die [J] . Causeret Frederic, Coppola Eva, Pierani Alessandra Current Opinion in Neurobiology . 2018,第期

机译：皮质发育死亡：选择生存或命中死亡
2. Why do they die? Comparison of selected aspects of organ injury and dysfunction in mice surviving and dying in acute abdominal sepsis [J] . Susanne Drechsler, Katrin M Weixelbaumer, Adelheid Weidinger, Intensive Care Medicine Experimental . 2015,第1期

机译：他们为什么死？急性腹部败血症中存活和死亡的小鼠器官损伤和功能障碍某些方面的比较
3. Hysterotomy and selective delivery of an intrauterine dead fetus to prevent intrauterine death or brain damage of the surviving fetus in monochorionic twin pregnancy. [J] . Ito T, Kadowaki K, Takahashi H, Journal of Perinatal Medicine . 1997,第1期

机译：子宫切开术和子宫内死胎的选择性分娩，以防止单绒毛膜双胎妊娠的子宫内死亡或幸存胎儿的脑损伤。
4. IMPACT OF HEALTH CARE EXPENDITURES ON DEATH RATES FOR SELECTED CAUSES OF DEATH IN CANADA, 1979-2003 [C] . Kenneth. H. Tiedemann Applied simulation and modelling . 2009

机译：1979-2003年加拿大卫生保健费用对某些死因致死率的影响
5. “Words survive”: Death and dying in women's letters [D] . Gallaway-Mitchell, Lee Anne 2008

机译：“言语得以生存”：妇女书信中的死亡和垂死
6. Why do they die? Comparison of selected aspects of organ injury and dysfunction in mice surviving and dying in acute abdominal sepsis [O] . Susanne Drechsler, Katrin M Weixelbaumer, Adelheid Weidinger, 2015

机译：他们为什么死？急性腹部败血症中存活和死亡的小鼠器官损伤和功能障碍某些方面的比较
7. Why do they die? Comparison of selected aspects of organ injury and dysfunction in mice surviving and dying in acute abdominal sepsis [O] . 2015

机译：他们为什么死？急性腹部败血症中存活和死亡的小鼠器官损伤和功能障碍某些方面的比较
8. Toxicity Studies of Selected Chemicals. Task II. The Developmental Toxicity of Vinylidene Chloride Inhaled by Rats and Mice during Gestation. [R] . short,robert d. jr minor,jan l. 1978

机译：选定化学品的毒性研究。任务二。大鼠和小鼠妊娠期吸入偏氯乙烯的发育毒性。

Cortical developmental death: selected to survive or fated to die

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