Changes in Speech Chunking in Reading Aloud is a Marker of Mild Cognitive Impairment and Mild-to-Moderate Alzheimer's Disease

De Looze Celine; Kelly Finnian; Crosby Lisa; Vourdanou Aisling; Coen Robert F.; Walsh Cathal; Lawlor Brian A.; Reilly Richard B.

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Changes in Speech Chunking in Reading Aloud is a Marker of Mild Cognitive Impairment and Mild-to-Moderate Alzheimer's Disease

机译：朗读语音分布的变化是一种轻度认知障碍和轻度至中度阿尔茨海默病的标志

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Background: Speech and Language Impairments, generally attributed to lexico-semantic deficits, have been documented in Mild Cognitive Impairment (MCI) and Alzheimer's disease (AD). This study investigates the temporal organisation of speech (reflective of speech production planning) in reading aloud in relation to cognitive impairment, particularly working memory and attention deficits in MCI and AD. The discriminative ability of temporal features extracted from a newly designed read speech task is also evaluated for the detection of MCI and AD.

机译：背景：言语和语言损伤通常归因于词典语义缺陷，以轻度认知障碍（MCI）和阿尔茨海默病（AD）记录。本研究调查了在与认知障碍中大声朗读，特别是MCI和广告中的记忆和注意力缺陷在大声朗读演讲（反映语言生产计划）的时间组织。还评估了从新设计的读语音任务中提取的时间特征的判别能力，用于检测MCI和AD。

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《Current Alzheimer research》 |2018年第9期|共20页
作者
De Looze Celine; Kelly Finnian; Crosby Lisa; Vourdanou Aisling; Coen Robert F.; Walsh Cathal; Lawlor Brian A.; Reilly Richard B.;
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作者单位

Trinity Coll Dublin Trinity Ctr Bioengn Sch Engn Dublin Ireland;

Trinity Coll Dublin Trinity Ctr Bioengn Sch Engn Dublin Ireland;

St James Hosp Mercers Inst Successful Ageing Dublin Ireland;

Trinity Coll Dublin Trinity Ctr Bioengn Sch Engn Dublin Ireland;

St James Hosp Mercers Inst Successful Ageing Dublin Ireland;

St James Hosp Mercers Inst Successful Ageing Dublin Ireland;

St James Hosp Mercers Inst Successful Ageing Dublin Ireland;

Trinity Coll Dublin Trinity Ctr Bioengn Sch Engn Dublin Ireland;

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原文格式 PDF
正文语种 eng
中图分类神经病学与精神病学;
关键词
Speech; timing; planning; working memory; markers; detection;

机译：言语;时间;规划;工作记忆;标记;检测;

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1. Changes in Speech Chunking in Reading Aloud is a Marker of Mild Cognitive Impairment and Mild-to-Moderate Alzheimer's Disease [J] . De Looze Celine, Kelly Finnian, Crosby Lisa, Current Alzheimer research . 2018,第9期

机译：朗读语音分布的变化是一种轻度认知障碍和轻度至中度阿尔茨海默病的标志
2. Cognitive and Functional Profiles in Mild-to-Moderate Alzheimer’s Disease and Mild Cognitive Impairment Compared to Healthy Elderly [J] . Mark Marsico, Celeste A. de Jager, April Grant, Advances in Alzheimer's Disease . 2014,第4期

机译：与健康老年人相比，轻度至中度阿尔茨海默氏病和轻度认知障碍的认知和功能特征
3. Visual Evaluation of Medial Temporal Lobe Atrophy as a Clinical Marker of Conversion from Mild Cognitive Impairment to Dementia and for Predicting Progression in Patients with Mild Cognitive Impairment and Mild Alzheimer's Disease [J] . Persson Karin, Barca Maria Lage, Eldholm Rannveig Sakshaug, Dementia and geriatric cognitive disorders . 2017,第1a2期

机译：中内颞叶萎缩的视觉评估作为痴呆症对痴呆症的临床标志物，用于预测轻度认知障碍患者的进展和轻度阿尔茨海默病
4. Detection of mild Alzheimer's disease and mild cognitive impairment from elderly speech: Binary discrimination using logistic regression [C] . Kato Shohei, Homma Akira, Sakuma Takuto, Annual International Conference of the IEEE Engineering in Medicine and Biology Society . 2015

机译：从老年人语音中检测轻度阿尔茨海默氏病和轻度认知障碍：使用逻辑回归的二元歧视
5. Oxidative stress in brain in mild cognitive impairment and early Alzheimer's disease: Implications for the progression of Alzheimer's disease. [D] . Reed, Tanea Tylette. 2007

机译：轻度认知障碍和早期阿尔茨海默氏病在大脑中的氧化应激：对阿尔茨海默氏病进展的影响。
6. Cognitive and Structural Correlates of Conversational Speech Timing in Mild Cognitive Impairment and Mild-to-Moderate Alzheimer’s Disease: Relevance for Early Detection Approaches [O] . Céline De Looze, Amir Dehsarvi, Lisa Crosby, 2021

机译：轻度认知障碍和温和至中等阿尔茨海默病中会话语音时序的认知和结构性相关性：早期检测方法的相关性
7. Cognitive and Functional Profiles in Mild-to-Moderate Alzheimer’s Disease and Mild Cognitive Impairment Compared to Healthy Elderly [O] . Mark Marsico, Celeste A. De Jager, April Grant, 2014

机译：与健康老年人相比，轻度至中度阿尔茨海默病和轻度认知障碍的认知和功能概况

Changes in Speech Chunking in Reading Aloud is a Marker of Mild Cognitive Impairment and Mild-to-Moderate Alzheimer's Disease

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