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Precision and accuracy of magnetic resonance imaging for lobar classification of benign prostatic hyperplasia

机译：良型前列腺增生的磁共振成像磁共振成像的精度和准确性

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Purpose To validate the application of a magnetic resonance imaging (MRI)-based lobar classification of benign prostatic hyperplasia (BPH) for use in research and clinical management. Methods Two radiologists with 5 and 11 years post-fellowship experience were trained in the lobar classification of BPH using an internally developed atlas of prostate anatomy with example MRI images edited by a third senior radiologist designated as the "administrator" of the study. A study population of 140 patients referred to a tertiary academic medical center with known or suspected prostate cancer was selected by the administrator to test the interrater reliability (IRR; precision) of the classification as well as accuracy of the two readers compared to the administrator as the "gold" standard. The intrarater reliability of repeat readings of the administrator was also examined. Percentage of agreement, proportion of agreement, and Cohen's κ were applied. This was a retrospective IRB-approved study. Results IRR (precision) between the two interpreting radiologists was 64% agreement, corresponding to unweighted κ of 0.52. Composite proportion of agreement across all BPH types (categories) for interpreting radiologists was 0.67. Observer accuracy was 62% agreement, unweighted κ 0.49, for observer 1 and 67%, unweighted κ 0.58, for observer 2. Intrarater reliability for the administrator was 87% agreement, unweighted κ 0.81 with composite proportion of agreement across all categories of 0.87. Conclusions MRI lobar classification of BPH is a reproducible and reliable tool for research and clinical applications.
机译：目的，用于验证磁共振成像（MRI）的应用，基于良性前列腺增生（BPH）的基洛达分类用于研究和临床管理。方法使用第三位前列腺解剖学的BPH的洛巴尔分类培训了两位有5和11年的放射科医生，使用前列腺解剖学与第三次高级放射科医生被指定为“管理员”的示例MRI图像。管理员选择了140名患者的140名患者，其中140名患者的第三学术医疗中心，涉及已知或疑似前列腺癌，以测试分类的Interrater可靠性（IRR;精度）以及与管理员相比的两个读者的准确性“金”标准。还检查了管理员重复读数的内在可靠性。应用协议，协议比例和科恩κ百分比。这是一个回顾性的IRB批准的研究。结果两位解释放射科医师之间的IRR（精确）是64％的协议，对应于0.52的未加权κ。解释放射科医师的所有BPH类型（类别）的综合综合比例为0.67。观察者准确性为62％的协议，未加权κ0.49，观察者1和67％，未加权κ0.58，用于观察者2.管理员的内在可靠性为87％的协议，未加权κ0.81，跨所有类别的综合比例为0.87。结论BPH的MRI Lobar分类是用于研究和临床应用的可重复且可靠的工具。

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