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首页> 外文期刊>Abdominal radiology. >Duodenal invasion by pancreatic adenocarcinoma: MDCT diagnosis of an aggressive imaging phenotype and its clinical implications
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Duodenal invasion by pancreatic adenocarcinoma: MDCT diagnosis of an aggressive imaging phenotype and its clinical implications

机译：十二指肠侵袭胰腺癌：MDCT诊断侵袭性成像表型及其临床意义

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Despite advances in oncologic and imaging technology, pancreatic ductal adenocarcinoma remains a highly deadly disease. The only curative option, pancreaticoduodenectomy or pancreatectomy, carries a significant morbidity. Current imaging plays a role in pre-operative staging to determine the probability of achieve disease-free margins. However, a small but not insignificant number of pancreatic cancers have a relatively higher aggressive biology, despite being resectable based on traditional criteria. Recently, imaging biomarkers that serve as a surrogate for tumors with such aggressive phenotype have been described. These include duodenal invasion and extrapancreatic perineural invasion. This review will focus on the former highlighting the summary of literature supporting duodenal invasion as a surrogate for aggressive disease as well as review its MDCT imaging features.
机译：尽管肿瘤和成像技术进展，但胰腺导管腺癌仍然是一种高度致命的疾病。 唯一的治疗方法，胰腺癌切除术或胰切除术，具有显着的发病率。 目前的成像在术前分期中起作用的作用，以确定实现无疾病利润率的可能性。 然而，尽管基于传统标准，但仍具有相对较高的侵略性生物学，胰腺癌具有相对较高的侵略性生物学。 最近，已经描述了作为具有这种侵袭性表型的蛋白蛋白蛋白蛋白的替代品的成像生物标志物。 这些包括十二指肠侵袭和外临时的麻纹侵袭。 本综述将侧重于前者突出摘要支持十二指肠入侵作为侵略性疾病的替代品的文献综述，以及审查其MDCT成像功能。

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