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Fat poor angiomyolipoma differentiation from renal cell carcinoma at 320-slice dynamic volume CT perfusion

机译:脂肪血小霉素缺乏血糖血滴瘤与320切片动态容积CT灌注的肾细胞癌分化

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摘要

Purpose To compare various CT perfusion features of fat poor angiomyolipoma (AML) with those of size-matched renal cell carcinoma (RCC). Methods One hundred and seventy-four patients [16 with fat poor AML (mean diameter, 3.1?cm; range, 1.5–5.5?cm) and 158 with RCC (mean diameter, 3.2?cm; range, 2.4–5.4?cm)] who had undergone 320-slice dynamic volume CT perfusion were evaluated. Equivalent blood volume ( BV ~(Equiv)), permeability surface-area product (PS), and blood flow (BF) of tumor were measured and analyzed. Fat poor AML was compared with each subtype of RCC (132 clear cell, 9 papillary, and 17 chromophobe). Receiver operating characteristic (ROC) curve analysis was performed for the comparison of fat poor AML and RCC. ROC curve analysis was not performed for the papillary RCC subtype because of the small number of masses of this subtype. Results BV ~(Equiv)and BF were significantly lower in fat poor AML than in clear cell RCC ( P ?
机译:目的,将脂肪贫困血管脂肪瘤(AML)的各种CT灌注特征与尺寸匹配的肾细胞癌(RCC)进行比较。方法1七十四名患者[16含脂肪差(平均直径,3.1×cm;范围,1.5-5.5厘米)和158,具有RCC(平均直径,3.2Ω厘米;范围,2.4-5.4?cm) [谁经历过320-切片动态体积CT灌注。测量并分析肿瘤的等效血容量(BV〜(EquIF)),渗透性表面积产品(PS)和血流(BF)。将脂肪差的AML与RCC的每个亚型进行比较(132个透明细胞,9粒乳头和17个发球)。对脂肪差AML和RCC的比较进行接收器操作特征(ROC)曲线分析。由于该亚型的少量群体,未对乳头状RCC亚型进行ROC曲线分析。结果BV〜(Equif)和BF在脂肪差的易粘度下显着低于透明细胞RCC(P?<β0.05)。脂肪差的AML具有较高的BV〜(Equiv),PS和BF而不是乳头状RCC(P?<β0.05)。 PS和BF在脂肪差的AML显着超过了发色体RCC(P?<β0.05)。对于从透明细胞RCC区分脂差差,BV〜(当量)和BF的ROC曲线(AUC)下的面积为0.82和0.69。使用最佳阈值,灵敏度,特异性,阳性预测值(PPV)和负预测值(NPV)为0.82,0.81,0.35,0.97,适用于BF的0.71,0.75,0.24,0.96,分别。为了将脂肪差的差,PS和BF的AUC分别为0.77和0.79。最佳敏感性,特异性,PPV和NPV分别为0.77,0.75,0.75,0.76,PS和0.71,0.81,0.72,0.80.80。结论脂肪差的AML和RCC的亚型在320切片动态容积CT下表现出不同的灌注特征,允许它们与BV〜(Equif),PS和BF的差异是有价值的灌注参数。

著录项

  • 来源
    《Abdominal radiology.》 |2018年第5期|共8页
  • 作者单位

    Department of Radiology PLA Army General Hospital;

    Department of Radiology Changhai Hospital of Shanghai The Second Military Medical University;

    Department of Radiology Changhai Hospital of Shanghai The Second Military Medical University;

    Department of Radiology Changhai Hospital of Shanghai The Second Military Medical University;

    Department of Neurology PLA Army General Hospital;

    Department of Orthopaedics Changhai Hospital of Shanghai The Second Military Medical University;

    Department of Radiology Changhai Hospital of Shanghai The Second Military Medical University;

    Department of Radiology PLA Army General Hospital;

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  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类 内科学;
  • 关键词

    Computed tomography; Perfusion imaging; Renal cell carcinoma; Fat poor angiomyolipoma;

    机译:计算断层扫描;灌注成像;肾细胞癌;脂肪贫血性血糖症;

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