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Suspicious breast lesions detected at 3.0 T Magnetic resonance imaging. Clinical and histological outcomes

机译：在3.0 T磁共振成像中检测到可疑乳房病变。 临床和组织学结果

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摘要

Rationale and Objectives: To evaluate the imaging features and histological and clinical outcomes of a series of suspicious, mammographically occult breast lesions detected at 3.0 T magnetic resonance imaging (MRI). Materials and Methods: Approval was obtained from the institutional review board. A Health Insurance Portability and Accountability Act-compliant retrospective review was performed of 121 suspicious, mammographically occult lesions detected on 3.0 T contrast-enhanced breast MRI. All 121 lesions underwent histological sampling. Radiology and clinic reports were reviewed for patient demographics, MRI indication and findings, biopsy and localization details, histological results, and follow-up information. Positive predictive value (PPV) of biopsy recommendations were calculated and compared for screening versus diagnostic cases. Likelihood of malignancy was also compared with lesion size. Statistical analyses were performed using chi-square, Fisher's exact, and two-tail z-tests. Results: Overall 43 malignancies were diagnosed from 121 suspicious, mammographically occult 3.0 T MRI-detected lesions. Seventy-eight (64%) of the 121 were benign. The overall PPV of 3.0 T MRI-detected lesions was 36% (43/121). The PPV for biopsy in the screening setting (22% [10/45]) was statistically significantly less (P = .018) compared to the PPV of a biopsy recommendation in the diagnostic setting (43% [33/76]). There was no correlation between lesion size and the likelihood of detecting malignancy. Conclusion: Our PPV of suspicious, mammographically occult, breast lesions detected at 3.0 T breast MRI is similar to the PPV reported previously for suspicious breast lesions detected at 1.5 T. This study supports the use of 3.0 T breast MRI for both screening and diagnostic breast imaging.
机译：理由和目标：评估在3.0T磁共振成像（MRI）的一系列可疑，乳房X射出乳房病变的成像特征和组织学和临床结果。材料和方法：从机构审查委员会获得批准。在3.0T对比增强的乳房MRI中检测到21个可疑的乳腺癌隐匿性病变，进行了健康保险便携性和责任行为符合的回顾性审查。所有121个病变接受了组织学抽样。对患者人口统计学，MRI指示和发现，活组织检查和本地化细节，组织学结果和后续信息进行了审查放射学和诊所报告。计算和比较活检推荐的阳性预测值（PPV），并比较筛查与诊断病例相比。也与病变大小进行了恶性肿瘤的可能性。使用Chi-Square，Fisher的精确和双尾Z测试进行统计分析。结果：总共43名恶性肿瘤被诊断为121名可疑，乳房X线爆发3.0 T MRI检测的病变。 121的七十八（64％）是良性的。 3.0 T mRI检测到的病变的总体ppv为36％（43/121）。与诊断设定中的活检推荐的PPV相比，筛选环境中的PPV（22％[10/45]）统计学显着较低（p = .018）（43％[33/76]）。病变大小与检测恶性肿瘤的可能性之间没有相关性。结论：我们的PPV可疑，乳房X XMAXCORALLY，3.0 T乳房MRI检测到的乳房病变类似于先前检测到的可疑乳腺病变的PPV，本研究支持3.0 T乳房MRI用于筛查和诊断乳房成像。

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  • 来源
    《Academic radiology》 |2012年第6期|共8页
  • 作者

    JohnsonK.S.; BakerJ.A.; LeeS.S.; SooM.S.;

  • 作者单位

    Duke University Medical Center DUMC 3808 Durham NC 27710 United States;

    Duke University Medical Center DUMC 3808 Durham NC 27710 United States;

    University of Chapel Hill Medical Center Chapel Hill NC United States;

    Duke University Medical Center DUMC 3808 Durham NC 27710 United States;

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  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类 放射医学;
  • 关键词

    Breast; Breast cancer; Breast MRI; Mammography; MRI;

    机译：乳房;乳腺癌;乳房MRI;乳房X线照相术;MRI;

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