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Low-dose, Prospective Triggered High-pitch Spiral Coronary Computed Tomography Angiography. Comparison with Retrospective Spiral Technique

机译:低剂量,前瞻性触发高位螺旋冠状动脉造影。 与回顾螺旋技术的比较

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摘要

Rationale and Objectives: Cardiac computed tomographic angiography algorithms emphasize radiation reduction while maintaining diagnostic image quality (IQ). The aim of this study was to evaluate IQ and interreader variability using prospective electrocardiographically triggered high-pitch spiral cardiac computed tomographic angiography (FLASH-CT) compared to retrospective electrocardiographic gating (RETRO-CT) for coronary artery disease evaluation in a patient population including overweight and obese individuals. Materials and Methods: Seventy patients (24 women; mean age, 60 years) matched for gender, age, body mass index (27.4 ± 5.5 kg/m 2), and calcium score (184 ± 328) underwent cardiac computed tomographic angiography, 35 with FLASH-CT (Definition Flash) and 35 with RETRO-CT (Somatom Definition). Images were reconstructed using standard protocols and least motion phase for RETRO-CT acquisitions. Two independent, blinded readers evaluated the coronary arteries using an 18-segment model, grading IQ on a 5-point, Likert-type scale and coronary stenosis on a 5-point semiquantitative and binary scale. Results: Effective radiation dose (1.50 vs 17.3 mSv, P .0001) and mean heart rate (58 vs 62 beats/min, P .05) were significantly lower for FLASH-CT compared to RETRO-CT. Seven hundred forty segments (1.5 mm) were evaluated. There was no significant difference between FLASH-CT and RETRO-CT scans in overall per-segment IQ (3.11 ± 0.75 vs 3.10 ± 0.82, P = .94). FLASH-CT had noninferior IQ relative to RETRO-CT (95% confidence interval, -0.25 to 0.26). There was no significant difference in interreader variability in diagnosis between FLASH-CT and RETRO-CT for all coronary segments (77.5% vs 78.2%, P = .83). Conclusions: FLASH-CT is an acceptable coronary computed tomographic angiographic method for reducing radiation dose without compromising IQ for a patient population including overweight and obese individuals.
机译:理由和目标:心脏计算断层血管摄像图算法强调辐射减少,同时保持诊断图像质量(IQ)。该研究的目的是使用前瞻性心电图触发的高位螺旋心脏计算机断层血管造影(Flash-CT)来评估IQ和Intereader变异性与患者人群中的冠状动脉疾病评估进行冠状动脉疾病评估(Retro-CT)相比,包括超重和肥胖的个人。材料和方法:七十名患者(24名女性;平均年龄,60岁)与性别,年龄,体重指数(27.4±5.5 kg / m 2),和钙得分(184±328)的心脏计算断层血管造影,35使用闪存-CT(定义闪光灯)和35带Reyro-CT(SOMATOM定义)。使用标准协议和最小运动阶段来重建图像进行复古-CT采集。两个独立的盲读者使用18段模型评估冠状动脉,在5点,李克尔特型规模和冠状动脉狭窄上进行了5分,冠状动脉狭窄的思考。结果:有效的辐射剂量(1.50 vs17.3msv,p& .0001)和平均心率(58 vs 62次/分钟,P&。05)对于闪蒸-ct与Ricro-CT相比显着降低。评估七百四十段(& 1.5 mm)。闪光-CT和Retro-CT扫描在整个每段IQ中没有显着差异(3.11±0.75 Vs 3.10±0.82,p = .94)。 Flash-CT相对于Recro-CT(95%置信区间,-0.25至0.26)具有非胰岛IQ。对于所有冠状动脉段(77.5%Vs 78.2%,P = .83),闪光-CT和Retro-CT之间的Intereader变异性诊断中没有显着差异。结论:Flash-CT是一种可接受的冠状动脉冠状动脉造影血管造影方法,用于减少辐射剂量,而不会影响患者患者群体,包括超重和肥胖个体。

著录项

  • 来源
    《Academic radiology》 |2012年第5期|共8页
  • 作者单位

    Department of Radiology New York University 550 First Avenue New York NY 10016 United States;

    Department of Radiology New York University 550 First Avenue New York NY 10016 United States;

    School of Medicine Department of Medicine Cardiology Division New York University 550 First;

    Department of Radiology University of Washington Seattle WA United States;

    Fraser Health Region Surrey BC Canada;

    Department of Radiology University of Arizona Tucson AZ United States;

    Department of Radiology New York University 550 First Avenue New York NY 10016 United States;

    Department of Radiology New York University 550 First Avenue New York NY 10016 United States;

    Department of Radiology New York University 550 First Avenue New York NY 10016 United States;

  • 收录信息
  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类 放射医学;
  • 关键词

    Coronary artery disease; Coronary CT angiography; Prospective gating; Radiation dose; Retrospective gating;

    机译:冠状动脉疾病;冠状动脉CT血管造影;未来门控;辐射剂量;回顾性门控;

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