Melkersson-Rosenthal Syndrome Successfully Treated With Adalimumab

de Moll Ellen H.; Lebwohl Mark G.

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Melkersson-Rosenthal Syndrome Successfully Treated With Adalimumab

机译：Melkersson-rosenthal综合征成功用Adalimumab治疗

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Melkersson-Rosenthal syndrome (MRS) is a rare syndrome of facial nerve palsy, facial edema, and lingua plicata that can be difficult to treat. We observed a patient with MRS of 4 years' duration that was unsuccessfully treated with multiple therapies. After a variety of diagnoses were considered at outside institutions, including Bell palsy, we diagnosed the patient with MRS based on clinical presentation of the classic triad. Treatment with adalimumab, a tumor necrosis factor alpha (TNF-alpha) antibody, showed improvement and relapse-free progress. Further research is needed regarding the role of TNF-alpha inhibitors in managing this rare condition.

机译：Melkersson-rosenthal综合征（MRS）是一种罕见的面神经麻痹，面部水肿和语气综合征，可能难以治疗。我们观察了患有4年持续时间的患者，这些持续时间不成功地用多种疗法治疗。在外部诊断局部诊断，包括贝尔麻痹，基于经典三合会的临床介绍，我们将患有MRS的患者。用Adalimalab治疗，肿瘤坏死因子α（TNF-α）抗体，显示出改善和无复发进展。关于TNF-α抑制剂在管理这种罕见病症方面的作用，需要进一步研究。

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《Cutis》 |2018年第2期|共3页
作者
de Moll Ellen H.; Lebwohl Mark G.;
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Icahn Sch Med Mt Sinai Dept Dermatol New York NY 10029 USA;

Icahn Sch Med Mt Sinai Dept Dermatol New York NY 10029 USA;

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正文语种 eng
中图分类皮肤病学与性病学;
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Melkersson-Rosenthal Syndrome Successfully Treated With Adalimumab

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