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Plantar Ulcerative Lichen P anus: Rapid Improvement With a Nove Triple-Therapy Approach

机译：Purtorar溃疡性地衣P肛门：用Nove三维治疗方法快速改进

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摘要

Ulcerative lichen planus (ULP) is a rare variant of lichen planus that is characterized by chronic, painful, and disabling ulcerations. Ulcerative lichen planus has been known to be resistant to many treatments, and therapeutic interventions often involve use of aggressive immunosuppressive medications without satisfactory remission of symptoms. We present the case of a 56-year-old man with an 8-year history of painful ulcerations on the right plantar foot as well as a large ulceration of the left lateral tongue. Biopsy confirmed a suspected diagnosis of plantar ULP. The patient developed marked clinical improvement of the cutaneous and oral mucosal lesions with oral and topical steroids, topical tacrolimus, and oral doxycycline after only 4 weeks of treatment. It is important for dermatologists to be aware of the potential diagnosis of plantar ULP, especially in the evaluation of chronic treatment-resistant ulcers that often have been previously misdiagnosed. We introduce this novel therapeutic regimen as a rapidly effective and relatively safe alternative to conventional immunosuppressive agents for long-term management of plantar ULP.
机译：溃疡性地衣平面（ULP）是一种罕见的地衣直升机的变体，其特征在于慢性，疼痛和溃疡。已知溃疡性地衣直升机对许多治疗有抵抗力，治疗干预往往涉及使用侵袭性免疫抑制药物，而不会令人满意的缓解症状。我们展示了一个56岁男性的案例，右侧溃疡的痛苦溃疡病史为8年历史，以及左侧舌头的大量溃疡。活组织检查证实了Puralar ULP的疑似诊断。患者在只有4周的治疗后，用口腔和局部类固醇，局部标准蛋白和口服卵黄素和口服粘膜和口服卵黄素的显着临床改善。对于皮肤科医生来说，要意识到Purtorar ULP的潜在诊断，特别是在评估慢性治疗的溃疡的评估中，这些抗性溃疡通常以前被误诊。我们将这种新的治疗方案介绍，作为常规免疫抑制剂的迅速有效且相对安全的替代品，用于Purtorar ULP的长期管理。

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