首页> 外文期刊>Acta biomaterialia >Effect of silica gel on the cohesion, properties and biological performance of brushite cement.
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Effect of silica gel on the cohesion, properties and biological performance of brushite cement.

机译:硅胶对黑盐水泥凝聚,性能和生物学性能的影响。

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The cohesion of calcium phosphate cements can be improved by the addition of substances to either the solid or liquid phase during the setting reaction. This study reports the effect of silica gel on brushite cement cohesion. The cement was prepared using a mixture of beta-tricalcium phosphate (beta-TCP) and monocalcium phosphate monohydrate as the solid phase, while the liquid phase comprised carboxylic acids silica gel. This cement presents a shorter final setting time (FST), better cohesion and higher amount of unreacted beta-TCP than the cement prepared without silica gel. Furthermore, in vivo experiments using rabbits as an animal model showed that after 8 weeks of implantation cements modified with silica gel showed a similar new bone formation volume and more remaining graft in comparison with unmodified cements. Thus, the silica gel could be efficiently applied to reduce cement disintegration and to decrease the resorption rate of brushite cements.
机译:通过在凝固反应期间,可以通过向固体或液相添加物质来提高磷酸钙水泥的内聚力。 本研究报告了硅胶对黑晶硅酸盐粘合的影响。 使用磷酸钙(β-TCP)的混合物制备水泥,作为固相的磷酸氨基钙,单水合物,而液相包括羧酸硅胶。 该水泥呈现较短的最终设定时间(FST),比没有硅胶制备的水泥更好的凝固时间(FST),更好的内聚力和更高量的未反应β-TCP。 此外,与动物模型的使用兔的体内实验表明,在用硅胶改性8周的植入水泥后,与未经修改的水泥相比,在用硅胶改性的植入水泥中显示出类似的新骨形成体积和更剩余的移植物。 因此,可以有效地施加硅胶以减少水泥崩解并降低黑铅矿水泥的吸收率。

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