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首页> 外文期刊>Acta gastro-enterologica Belgica >Endoscopic submucosal multi-tunnel dissection for large early esophageal cancer lesions
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Endoscopic submucosal multi-tunnel dissection for large early esophageal cancer lesions

机译：大型早期食管癌病变的内窥镜粘膜分析

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摘要

Objective : To evaluate the safety and efficacy of endoscopic submucosal multi-tunnel dissection (ESMTD) for early esophageal cancer lesions larger than 3 cm in diameter or cumulatively greater than 1/2 lumen size. Method : Early esophageal cancer lesions in 15 patients were detected by endoscopy and endoscopic ultrasonography in our endoscopy center from December 2012 to June 2015. All lesions were successfully resected by ESMTD and diagnosed by pathology, and therapeutic efficiency and safety were followed after surgery. Results : All 15 of the early esophageal cancer lesions were resected by ESMTD. The pathological results showed 9 moderately differentiated and 6 highly differentiated squamous cell carcinomas. En bloc resection was achieved in 13 lesions, with negative lateral and basal margins on pathology, whereas the other 2 required additional surgery. The average diameter of the resected lesions was 4.2±0.9 cm. The mean procedure time was 94.7±52.9 min. Esophageal stenosis was observed in 7 patients for whom esophageal water balloon dilatation was performed. No residual or recurrent lesion was found during the 6-36-month follow-up period. Conclusion: ESMTD is a safe and efficient technique for treating large early esophageal cancer lesions. Grasping the key techniques of this procedure can reduce operating difficulty and shorten the operating time.
机译：目的：评价内窥镜粘膜粘膜的安全性和有效性多隧道分布（ESMTD），用于早期食道癌病变大于3厘米或累积大于1/2腔大小。方法：2012年12月至2015年6月，通过内窥镜检查中心内窥镜检查和内窥镜超声检测到15名患者的早期食管癌病变。所有病变均由ESMTD成功切除，并通过病理学诊断，手术后进行治疗效率和安全性。结果：ESMTD切除了所有早期食管癌病变。病理结果表明，9个中度分化和6个高度分化的鳞状细胞癌。 en Bloc切除在13个病变中实现，具有负面的横向和基础余量，而另外2则需要额外的手术。切除病变的平均直径为4.2±0.9厘米。平均程序时间为94.7±52.9分钟。在7名患者中观察到食管狭窄，为食管水球囊扩张进行了患者。在6-36个月的随访期间没有发现残留或复发性病变。结论：ESMTD是一种治疗大型早期食管癌病变的安全有效的技术。掌握此过程的关键技术可以减少操作难度并缩短操作时间。

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