首页> 外文期刊>Acta gastro-enterologica Belgica >The role of the pathologist and clinical implications in colorectal liver metastasis
【24h】

The role of the pathologist and clinical implications in colorectal liver metastasis

机译:病理学家的作用和临床意义在结肠直肠肝转离症中

获取原文
获取原文并翻译 | 示例
           

摘要

Colorectal liver metastases (CRLM) affect about 50% of colorectal cancer patients. With the improvement of neoadjuvant chemotherapy and the introduction of targeted therapy, resectability of CRLM and survival rates have improved over time. However, 60-70% of patients still recur. Several pathological and molecular parameters have been described as prognostic factors after CRLM resection. These parameters encompass not only tumoral features, but also non-tumoral ones, such as chemotherapy related liver injury, or factors related to tumour environment, namely Immunoscore. This review summarizes these prognostic indicators to clarify which patho-molecular parameters should be addressed in the pathological report. (Acta Gastroenterol. belg., 2018, 81, 419-426).
机译:结肠直肠肝转移(CRLM)影响约50%的结肠直肠癌患者。 随着Neoadjuvant化疗的改善和靶向治疗的引入,CRLM的可分离性和生存率随着时间的推移而得到改善。 然而,60-70%的患者仍然会发生重搏。 在CRLM切除后,几种病理和分子参数被描述为预后因素。 这些参数不仅包括肿瘤特征,还包括非肿瘤的特征,例如化疗相关肝损伤,或与肿瘤环境相关的因素,即免疫审核。 本综述总结了这些预后指标,阐明了应在病理报告中解决了哪些差分分子参数。 (Acta Gastroenterol。Belg。,2018,81,419-426)。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱:kefu@zhangqiaokeyan.com

京公网安备:11010802029741号 ICP备案号:京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有
  • 客服微信

  • 服务号