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Comparison of conventional, diffusion, and perfusion MRI between infratentorial ganglioglioma and pilocytic astrocytoma

机译:植物甘蓝叶瘤和铅胶质细胞星状细胞瘤之间的常规,扩散和灌注MRI的比较

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Background The differentiation of infratentorial ganglioglioma and pilocytic astrocytoma may be therapeutically relevant, which is sometimes challenging to both pathologists and neuroradiologists. Purpose To evaluate the conventional magnetic resonance imaging (MRI), diffusion-weighted imaging (DWI), and dynamic susceptibility contrast-enhanced perfusion weighted imaging (DSC-PWI) features of infratentorial ganglioglioma compared with pilocytic astrocytoma. Material and Methods This retrospective study enrolled 12 patients with infratentorial ganglioglioma and 61 patients with pilocytic astrocytoma who underwent MRI before surgery. DSC-PWI was performed in 20 patients (4 gangliogliomas, 16 pilocytic astrocytoma). Demographics, conventional imaging characteristics (tumor location, margin, cystic change, enhancement, peritumoral edema, and ipsilateral cerebellar atrophy), rADC(min), and rCBV(max) ratio were compared. The optimum threshold, sensitivity, and specificity for rADC(min) and rCBV(max) ratios were determined. Results Infratentorial ganglioglioma appeared similar to pilocytic astrocytoma but was more likely to have an ill-defined margin (P = 0.035), ipsilateral cerebellar atrophy (P 1.64. Conclusion Conventional MRI, DWI, and DSC-PWI can help to differentiate infratentorial ganglioglioma from pilocytic astrocytoma. DWI offers optimal sensitivity.
机译:背景技术Infratential Ganglioglioma和Plipyytic星形细胞瘤的分化可能治疗相关,这有时对病理学家和神经产物学家有时挑战。目的是评估常规磁共振成像(MRI),扩散加权成像(DWI),与鳞状不经症星形细胞瘤相比,Infratential Ganglioglioma的动态敏感性对比增强灌注加权成像(DSC-PWI)特征。材料和方法本回顾性研究注册了12名Infratential Ganglioglioma患者和61例患有手术前MRI的盗贼星形细胞瘤的61名患者。 DSC-PWI在20名患者中进行(4名Gangliogliomas,16个盗集星形细胞瘤)。比较了人口统计学,传统成像特性(肿瘤位置,边缘,囊性变化,增强,腹腔水肿和同侧萎缩),Radc(min)和RCBV(MAX)比。确定Radc(min)和RCBV(MAX)比的最佳阈值,灵敏度和特异性。结果Infratential Ganglioglioma类似于硫脲星形细胞瘤,但更容易具有明确的边缘(p = 0.035),即Ipsilidal脑萎缩(P 1.64。结论常规MRI,DWI和DSC-PWI可以帮助利用盗贼分离来自盗贼星形细胞瘤。DWI提供最佳敏感性。

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