Dimethyl sulfoxide-induced dehydration of the intermembrane space of dipalmitoylphosphatidylcholine multilamellar vesicles: Neutron and synchrotron diffraction study

Kiselev M. A.; Zemlyanaya E. V.

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Dimethyl sulfoxide-induced dehydration of the intermembrane space of dipalmitoylphosphatidylcholine multilamellar vesicles: Neutron and synchrotron diffraction study

机译：二甲基亚砜诱导的二硫代酰基磷脂磷胆碱囊泡膜空间的脱水：中子和同步调节衍射研究

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Small-angle neutron scattering spectra of a polydispersed population of dipalmitoylphosphatidylcholine (DPPC) unilamellar vesicles in heavy water in the presence of dimethyl sulfoxide (DMSO) are analyzed by means of the separated form-factor method. An increase in the mole fraction of DMSO in water from 0 to 15% was shown to lead to an increase in the thickness of the bilayer to the characteristics repeat distances of DPPC multilamellar membranes. This fact is indicative of dehydration of the intermembrane space and a steric contact between adjacent DPPC bilayers at 15% mole fraction of DMSO.

机译：通过分离的形式因子法分析在二甲基亚砜（DMSO）存在下重水中的多普利酰基磷脂酰胆碱（DPPC）Unilamellar囊泡的小角中子散射光谱进行分析。显示从0至15％水中DMSO的摩尔级分的增加导致双层厚度增加到DPPC多层膜的特性重复距离。这一事实表明脱水的膜间空间和相邻的DPPC双层之间的空间接触，在15％的DMSO中摩尔分数。

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《Crystallography reports》 |2017年第5期|共5页
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Kiselev M. A.; Zemlyanaya E. V.;
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Joint Inst Nucl Res Dubna 141980 Moscow Region Russia;

Joint Inst Nucl Res Dubna 141980 Moscow Region Russia;

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正文语种 eng
中图分类晶体学;
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1. Dimethyl sulfoxide-induced dehydration of the intermembrane space of dipalmitoylphosphatidylcholine multilamellar vesicles: Neutron and synchrotron diffraction study [J] . Kiselev M. A., Zemlyanaya E. V. Crystallography reports . 2017,第5期

机译：二甲基亚砜诱导的二硫代酰基磷脂磷胆碱囊泡膜空间的脱水：中子和同步调节衍射研究
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6. Effects of the anesthetic dibucaine on the kinetics of the gel-liquid crystalline transition of dipalmitoylphosphatidylcholine multilamellar vesicles. [O] . W W van Osdol, Q Ye, M L Johnson, 1992

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Dimethyl sulfoxide-induced dehydration of the intermembrane space of dipalmitoylphosphatidylcholine multilamellar vesicles: Neutron and synchrotron diffraction study

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