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Depression and anxiety mediate perceived social support to predict health-related quality of life in pregnant women living with HIV

机译:抑郁和焦虑调解感知社会支持,以预测艾滋病病毒妇女的孕妇与健康有关的生活质量

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Pregnant women living with HIV represent one of the most high-priority groups for HIV treatment and health assessment. Although social support has been shown to be a protective factor for improved health-related quality of life (HRQoL), and depression and anxiety have been identified as two major causes of psychological distress among people living with HIV, it is still unclear how social support, anxiety, and depression interact to influence HRQoL. The objective of our study was to demonstrate the nature of predictors, direct effects and mediator effects among social support, anxiety, depression symptoms and HRQoL in pregnant women living with HIV. We investigated a total of 101 pregnant women living with HIV in Yunnan province in China from April 2016 to June 2016. All participants completed the Social Support Rating Scale (SSRS), the Chinese version of the Hospital Anxiety and Depression Scales (HADS) and Quality of Life instruments (EuroQoL Five Dimensions Questionnaire, EQ-5D). The relationships between the variables were examined by Pearson's or Spearman's correlation analysis. Predictor effects were tested using separate multiple regressions, controlling for demographic variables and HIV diagnosis variables. Direct and mediation effects of social support on HRQoL were tested using a structural equation model (SEM). Anxiety and depression symptoms were negatively correlated with subjective social support, support utilization, social support and HRQoL. Social support significantly predicted better HRQoL, and anxiety and depression symptoms significantly predicted poorer HRQoL. Anxiety and depression symptoms partially mediated the associations between social support and HRQoL. Anxiety and depression symptoms completely mediated the associations of objective support and support utilization with HRQoL. Interventions to improve HRQoL in pregnant women living with HIV must consider the mediation effect of anxiety and depression symptoms on the association between social support and HRQoL. Social support interventions are valid only when anxiety and depression symptoms are managed effectively.
机译:艾滋病病毒症的孕妇代表了艾滋病毒治疗和健康评估中最高级的群体之一。虽然社会支持被证明是改善健康相关生活质量(HRQOL)的保护性因素,但抑郁和焦虑已经被确定为与艾滋病毒患有艾滋病毒的人们的心理窘迫的两个主要原因,但仍然不清楚社会支持如何,焦虑和抑郁症相互作用影响HRQOL。我们研究的目的是展示患有艾滋病毒患者的孕妇的社会支持,焦虑,抑郁症状和HRQOL之间的预测因子,直接影响和调解症状的性质。从2016年4月到2016年6月,我们调查了云南省艾滋病毒艾滋病毒的孕妇。所有参与者完成了社会支持评级规模(SSRS),中文版医院焦虑和抑郁症(曾经)和质量生命仪器(Euroqol五维问卷调查表,EQ-5D)。由Pearson或Spearman的相关分析检查了变量之间的关系。使用单独的多元回归测试预测效应,控制人口统数变量和HIV诊断变量。使用结构方程式模型(SEM)测试社会支持对HRQOL的直接和调解效果。焦虑和抑郁症状与主观社会支持,支持利用,社会支持和HRQOL负面相关。社会支持显着预测更好的HRQOL,焦虑和抑郁症状明显预测HRQOL较差。焦虑和抑郁症状部分地调解了社会支持与HRQOL之间的协会。焦虑和抑郁症状完全介绍了客观支持的协会,并与HRQOL的支持。改善艾滋病病毒症患者的孕妇的干预措施必须考虑焦虑和抑郁症状对社会支持与HRQOL之间的关联的调解效应。只有在有效管理焦虑和抑郁症状时,社会支持干预才有效。

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