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首页> 外文期刊>AIDS care. >Excess costs of non-infectious comorbidities among people living with HIV - estimates from Denmark and Sweden
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Excess costs of non-infectious comorbidities among people living with HIV - estimates from Denmark and Sweden

机译：与艾滋病毒艾滋病毒患者的人们之间的非传染性合并的过度成本 - 丹麦和瑞典的估计

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People living with HIV have an increased risk of comorbidities with non-communicable diseases such as cardiovascular disease, chronic kidney disease and osteoporotic fractures, compared to the general population. The burden of these comorbidities is expected to rise as the HIV-infected population ages. This development may require additional health care resources and it is relevant to ascertain the costs associated with these comorbidities. The population attributed risk approach was applied to estimate excess costs associated with the higher rates of comorbidities among HIV patients in Denmark and Sweden compared to their respective general populations. Excess direct and indirect costs for one year were calculated for myocardial infarction, stroke, osteoporotic fractures and chronic kidney disease. Cost estimates were presented in age and sex subgroups. In the course of one year the excess costs for myocardial infarction, stroke, osteoporotic fractures and chronic kidney disease attributable to HIV was estimated to Euro3.4 million for Denmark and Euro2.6 million for Sweden. Chronic kidney disease accounted for the majority of the total excess costs, followed by osteoporotic fractures, myocardial infarction and stroke. The high prevalence of comorbidities in the HIV-infected population is associated with substantial excess costs. Focus on primary and secondary prophylactic interventions is warranted. Additional studies, preferably large-scale case-control studies, may give further insights on the extent and the predictors of these excess costs.
机译：与普通人群相比，艾滋病毒患有艾滋病毒的人具有增加的非传染性疾病，如心血管疾病，慢性肾病和骨质疏松骨折。预计这些合并症的负担将随着艾滋病毒感染的人群年龄而上升。这种发展可能需要额外的保健资源，并确定与这些合并症相关的成本是相关的。拟合人口归属风险方法估计与丹麦和瑞典的艾滋病患者较高的多余成本估计与瑞典相比各自的一般人口相比。为心肌梗死，中风，骨质疏松骨折和慢性肾病计算一年的过度直接和间接成本。成本估计呈现在年龄和性别亚组。在一年的过程中，对艾滋病毒的心肌梗死，中风，骨质疏松骨折和慢性肾脏疾病的过剩成本估计为丹麦的欧元340万欧元，瑞典为欧元2.6百万。慢性肾病占大多数总产量的成本，其次是骨质疏松骨折，心肌梗死和中风。艾滋病病毒感染群体中的合并性高的患病率与大量超额成本有关。重点关注初级和二级预防性干预措施。额外的研究，优选大规模的病例对照研究，可以进一步了解这些超额成本的程度和预测因子。

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