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HIV Infection in North African Patients

机译：北非患者的艾滋病毒感染

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North Africa is one of the rare regions where the HIV epidemic is growing. In France, 5% of the migrants discovering their HIV infection are from North Africa. The objective of this study was to compare the sociodemographic characteristics and outcomes of North African and French HIV-infected patients. This study was conducted in the HIV clinic of Bichat Hospital (Paris, France). The North African HIV-infected patients were born in Algeria, Tunisia, or Morocco or had lived there for more than 6 months. They were matched for age and gender (1:2) to patients born in France who had never lived outside France for more than 6 months. Sociodemographic, clinical, and immunovirological characteristics of North African and French patients were compared using conditional logistic regression. Among 4,738 eligible patients, 285 North Africans were identified. CD4 levels at HIV diagnosis were not significantly different between North African and French patients, but were more frequently <200/mm(3) in the former than the latter at treatment initiation (p = .02). CDC stage 3 disease occurred more frequently in the first 3 years of care in our center in North African patients than in French patients (p = .01), and control of the HIV viral load over the 12 months preceding inclusion was better in French patients (p = .0001). There was no difference regarding loss to care. These results highlight possible issues in adherence to antiretroviral treatment in North African patients, which may be related to differences in the acceptability of the disease.
机译：北非是艾滋病毒流行的罕见地区之一。在法国，5％的移民发现他们的艾滋病毒感染来自北非。本研究的目的是比较北非和法国艾滋病毒感染患者的社会渗塑特征和结果。该研究是在Bichat医院（法国巴黎）的HIV诊所进行的。北非艾滋病毒感染的患者出生于阿尔及利亚，突尼斯或摩洛哥，或者在那里居住了6个多月。它们与年龄和性别（1：2）与在法国出生的患者中匹配，患者从未在法国以外以外超过6个月。使用条件逻辑回归比较了北非和法国患者的社会阶段，临床和免疫病毒学特征。在4,738名符合条件的患者中，确定了285名北非人。哈维病毒诊断的CD4水平在北非和法国患者之间没有显着差异，但前者比治疗开始的后者更频繁地<200 / mm（3）（p = .02）。 CDC阶段3疾病发生在我们的中心在我们的北非患者中的前3年的疾病比法国患者（P = .01），并控制艾滋病病毒病毒载量前12个月，前一种含有的法国患者更好（p = .0001）。有关要关心的损失没有差异。这些结果突出了北非患者抗逆转录病毒治疗中可能存在的问题，这可能与疾病可接受性的差异有关。

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