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首页> 外文期刊>Alcohol >Enhanced erythrocyte antioxidant status following an 8-week aerobic exercise training program in heavy drinkers
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Enhanced erythrocyte antioxidant status following an 8-week aerobic exercise training program in heavy drinkers

机译：在沉重的饮酒者8周的有氧运动训练计划之后提高红细胞抗氧化状态

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Alcohol-induced oxidative stress is involved in the development and progression of various pathological conditions and diseases. On the other hand, exercise training has been shown to improve redox status, thus attenuating oxidative stress-associated disease processes. The purpose of the present study was to evaluate the effect of an exercise training program that has been previously reported to decrease alcohol consumption on blood redox status in heavy drinkers. In a non-randomized within-subject design, 11 sedentary, heavily drinking men (age: 30.3?±?3.5 years; BMI: 28.4?±?0.86?kg/m2) participated first in a control condition for 4 weeks, and then in an intervention where they completed an 8-week supervised aerobic training program of moderate intensity (50–60% of the heart rate reserve). Blood samples were collected in the control condition (pre-, post-control) as well as before, during (week 4 of the training program), and after intervention (week 8 of the training program). Samples were analyzed for total antioxidant capacity (TAC), thiobarbituric acid reactive substances (TBARS), protein carbonyls (PC), uric acid (UA), bilirubin, reduced glutathione (GSH), and catalase activity. No significant change in indices of redox status in the pre- and post-control was observed. Catalase activity increased (p?
机译：醇诱导的氧化应激参与各种病理条件和疾病的发展和进展。另一方面，已经显示运动培训来改善氧化还原状态，从而衰减氧化应激相关的疾病过程。本研究的目的是评估先前据报道的锻炼培训计划的效果，以减少重饮料中的血氧化还原地位的酒精消耗。在一个非随机的主题设计中，11个久坐不动，饮用男性（年龄：30.3？±3.5岁; BMI：28.4？±0.86？Kg / M2）首先在控制条件下参加4周，然后在他们完成8周监督的中等强度的8周监督的干预中（占心率储备的50-60％）。在控制条件下收集血样（预防，后控制）以及之前（培训计划第4周），干预后（培训计划的第8周）。分析样品的总抗氧化能力（TAC），硫酰碱酸反应性物质（TBARS），蛋白质羰基（PC），尿酸（UA），胆红素，降低的谷胱甘肽（GSH）和过氧化氢酶活性。观察到在预先控制和控制后氧化还原状态指数没有重大变化。与第4周相比，过氧化氢酶活性增加（p？<β05）在8周的干预后8周的时间增加TAC，UA，Bilirubin，TBAR和PC在任何时间点都没有显着变化。此外，GSH，TBAR和过氧化氢酶活性与醇消耗负相关的浓度。总之，8周的有氧训练计划增强了重型饮酒者的红细胞抗氧化状态，表明有氧训练可能衰减由醇诱导的氧化应激引起的病理过程。

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