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Borderline personality disorder symptoms in treatment-na?ve actively drinking alcoholics

机译：邻近人格障碍治疗症状-NA？VE积极饮酒酗酒者

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Borderline personality disorder (BPD) is often a complicating comorbid factor in alcohol use disorders and substance use disorders. Previous work showed that abstinent alcoholics endorsed lifetime and current symptoms of most of the BPD criteria at much higher rates than controls, with much higher symptom counts for short-term abstinent alcoholic (STAA) women than men, which is consistent with such symptoms negatively affecting female alcoholics' ability to maintain abstinence. Because prior work has also shown that treatment-na?ve alcoholics (TNA) are not the same as treated alcoholics observed earlier in their alcohol dependence, but rather are a different population with potentially lower psychiatric comorbidity, in this study we compared BPD symptom criteria between TNA samples of comparable age to the control and STAA samples, including both men and women and individuals dependent on alcohol only or with lifetime dependence on both alcohol and drugs. BPD symptoms were obtained using the SCID-II, and endorsed symptoms were classified as current or lifetime. Logistic regression analyses were used to test for effects of group, sex, presence of a lifetime drug dependence diagnosis, and their interactions for lifetime and current symptom endorsement for each BPD criteria. Groups were compared pairwise (TNA vs. NSAC, and STAA vs. TNA). The effect of a lifetime drug dependence diagnosis was not significant for any BPD symptom variable, consistent with the alcohol groups’ BPD symptoms being unaffected by the presence of a comorbid drug dependence. The primary result presented here is that TNA women have borderline symptomatology more similar to that of treated STAA than to NSAC, while TNA men have borderline symptomatology more similar to NSAC than to STAA. A visual examination of co-occurring BPD symptoms showed that while more BPD symptoms are likely to be present in TNA and STAA vs. NSAC, there is no grouping of criteria (i.e., symptom cluster) that is characteristic of TNA or STAA.
机译：边界人格障碍（BPD）通常是酒精使用障碍和物质使用障碍的复杂性因子。以前的工作表明，幅度的酗酒者应认可的寿命和目前大多数BPD标准的症状，比对照率更高，症状数量与男性相比，短期围困醇（STAA）女性的症状计数大得多，这与对这种症状产生负面影响的症状女性酗酒者维持禁欲的能力。因为前工作也表明，治疗毒液（TNA）与早期观察到的酒精依赖性观察到的酗酒者不同，但在这项研究中，我们比较了潜在的较低的精神病患者的不同人群，我们比较了BPD症状标准在对照和STAA样本的可比年龄的TNA样本之间，包括男性和女性和个体依赖于酒精或终身依赖酒精和药物。使用SCID-II获得BPD症状，并且应被归属症状被归类为电流或寿命。物流回归分析用于测试组，性别，终身药物依赖诊断的效果，以及它们对每个BPD标准的寿命和目前症状认可的相互作用。将基团进行比较（TNA与NSAC和STAA与TNA）进行比较。寿命药物依赖性诊断的效果对于任何BPD症状变量并不重要，与酒精组的BPD症状一致不受经链肥药物依赖性的影响。这里呈现的主要结果是TNA女性具有边缘症状，更类似于对待STAA而不是NSAC的症状，而TNA男性则与NSAC更类似于NSAC而不是SAA。视觉检查同期的BPD症状表明，虽然TNA和STAA与NSAC中有更多的BPD症状，但没有分组是TNA或STAA的特征的标准（即症状簇）。

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