mTORC2 controls Th9 polarization and allergic airway inflammation

Chen H.; Wang P.; Su H.; Wang W.; Chu Z.; Zhang L.; Zhang X.; Zhao Y.

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mTORC2 controls Th9 polarization and allergic airway inflammation

机译：MTORC2控制TH9极化和过敏气道炎症

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摘要

Background: T helper type 9 (Th9) cells, a subpopulation of CD4(+) T cells, play a critical role in the pathogenesis of allergic airway inflammation. However, it remains unknown whether mTORC2 regulates Th9 differentiation or function during allergic inflammation.

机译：背景：T辅助型9（TH9）细胞，CD4（+）T细胞的亚群，在过敏气道炎症的发病机制中发挥着关键作用。然而，它仍然未知MTORC2是否调节过敏炎症期间的分化或功能。

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来源
《Allergy》 |2017年第10期|共11页
作者
Chen H.; Wang P.; Su H.; Wang W.; Chu Z.; Zhang L.; Zhang X.; Zhao Y.;
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作者单位

Chinese Acad Sci Inst Zool State Key Lab Membrane Biol Transplantat Biol Res Div Beijing;

Chinese Acad Sci Inst Zool State Key Lab Membrane Biol Transplantat Biol Res Div Beijing;

Chinese Acad Sci Inst Zool State Key Lab Membrane Biol Transplantat Biol Res Div Beijing;

Capital Med Univ Beijing Chaoyang Hosp Dept Urol Beijing Peoples R China;

Chinese Acad Sci Inst Zool State Key Lab Membrane Biol Transplantat Biol Res Div Beijing;

Minist Hlth Key Lab Human Dis Comparat Med Beijing Peoples R China;

Capital Med Univ Beijing Chaoyang Hosp Dept Urol Beijing Peoples R China;

Chinese Acad Sci Inst Zool State Key Lab Membrane Biol Transplantat Biol Res Div Beijing;

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原文格式 PDF
正文语种 eng
中图分类医学免疫学;
关键词
allergy; asthma; mTOR; Rictor; Th9 cells;

机译：过敏;哮喘;MTOR;RICTOR;TH9细胞;

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专利

1. mTORC2 controls Th9 polarization and allergic airway inflammation [J] . Chen H., Wang P., Su H., Allergy . 2017,第10期

机译：MTORC2控制TH9极化和过敏气道炎症
2. Lower airways inflammation in allergic rhinitics: a comparison with asthmatics and normal controls. [J] . Brown JL, Behndig AF, Sekerel BE, Clinical and experimental allergy : . 2007,第5期

机译：过敏性鼻炎患者的下呼吸道炎症：与哮喘患者和正常对照组的比较。
3. The Allergic Airway Inflammation Repository - A user-friendly, curated resource of mRNA expression levels in studies of allergic airways [J] . GawelD.R., RaniJamesA., BensonM., Allergy . 2014,第8期

机译：过敏性气道炎症储存库-过敏性气道研究中一种易于使用的精选mRNA表达水平资源
4. Effects of Asian Sand Dust on Allergic Airway Inflammation in Mice [C] . Takamichi Ichinose, Miao HE, Seiichi Yoshida, Conference on Environmental Pollution and Public Health . 2012

机译：亚洲沙尘对小鼠过敏性气道炎症的影响
5. The Effects of Particulate Matter Exposure During Allergic Sensitization in an Acute Murine Model of Allergic Airway Inflammation. [D] . Carosino, Christopher Michael. 2012

机译：在急性气道炎症急性小鼠模型中，过敏致敏过程中颗粒物暴露的影响。
6. Gut dysbiosis promotes M2 macrophage polarization and allergic airway inflammation via fungi-induced PGE2 [O] . Yun-Gi Kim, Kankanam Gamage Sanath Udayanga, Naoya Totsuka, -1

机译：肠道营养不良通过真菌诱导的PGE2促进M2巨噬细胞极化和过敏性气道炎症
7. The amino acid sensor general control nonderepressible 2 (GCN2) controls TH9 cells and allergic airway inflammation [O] . Peng Wang, Yana Xu, Jiayu Zhang, 2019

机译：氨基酸传感器一般控制非胶版2（GCN2）对照TH9细胞和过敏气道炎症

mTORC2 controls Th9 polarization and allergic airway inflammation

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