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首页> 外文期刊>Allergy >Indoor allergen levels in settled airborne dust are higher in day‐care centers than at home
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Indoor allergen levels in settled airborne dust are higher in day‐care centers than at home

机译：在沉淀的空气中尘埃的室内过敏原水平在日间中心较高，而不是家

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摘要

Abstract Background Early‐life sensitization to indoor allergens predicts asthma development. The aim of this study was to compare allergen concentrations in day‐care centers ( DCC ) with those in private homes. Methods Settled airborne dust was collected 4 times a year from 20 German DCC (620 samples) and from the homes of children and day‐care workers (602 samples) using electrostatic dust collectors ( EDC ). The samples were analyzed with fluorescence enzyme immunoassays recognizing domestic mite allergens ( DM ), Fel d 1, Can?f 1, and Mus m 1. Pet?allergen thresholds that discriminate samples from homes with cats or dogs from those without were calculated using receiver‐operating characteristics. Influences on allergen levels were analyzed using multilevel models. Results Allergen loads were on average higher in DCC than in homes. In DCC , 96% of the samples were positive for DM , 95% for Can f 1, 90% for Fel?d 1, and 83% for Mus?m 1. In homes, 84% contained DM , 48.5% Can?f 1, 33% Fel?d 1, and 43% Mus?m 1. The threshold level for homes with dogs was 75?ng/m2 Can?f 1 (96.8% sensitivity, 96% specificity), and the threshold level for homes with cats was 46?ng/m2 Fel?d 1 (92% sensitivity, 94.9% specificity). In DCC , Can f 1 and Fel d 1 loads were higher than these thresholds in 37% and 54% of the samples, respectively. Allergen levels were significantly influenced by the season and room type; however, carpets on floors had no influence. Conclusions Mite, mouse, cat, and dog allergens were mostly higher in DCC than in homes. Exposure to dog and cat allergens in DCC often reached levels of households with pets.
机译：摘要背景过敏原的早期敏感性预测哮喘发育。本研究的目的是将日托中心（DCC）与私人住宅中的过敏原浓度进行比较。方法从20名德国DCC（620个样品）和儿童家庭和日间护理工作者（602样品）的静电集尘器（EDC）收集4次，每年收集4次空气灰尘。用荧光酶免疫测定分析样品，识别家用螨虫过敏原（DM），FEL D 1，CAN-F 1和MUS M 1. PET？过敏原阈值，以使用接收器计算来自猫或狗的猫或狗的家庭的样品 - 操作特征。使用多级模型分析对过敏原水平的影响。结果过敏原载荷在DCC平均高于房屋。在DCC中，96％的样品对于DM阳性，95％，对于FEC的F 1,90％，90％，肌肉83％，83％的MUS？M 1.在房屋中，84％含有DM，48.5％CAN？F 1,33％的Fel？D 1和43％MUS？M 1.与狗的家庭的阈值水平为75？NG / M2可以？F 1（灵敏度为96％的特异性96％），以及房屋的阈值水平猫是46°？ng / m2 fel？d 1（灵敏度为94.9％的特异性）。在DCC中，可以分别在37％和54％的样品中高于这些阈值。过敏原水平受季节和房间类型的显着影响;然而，地板上的地毯没有影响力。结论DCC的螨虫，小鼠，猫和狗过敏原小于家庭。暴露于DCC的狗和猫过敏原经常达到宠物的家庭水平。

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  • 来源
    《Allergy》 |2018年第6期|共13页
  • 作者

    Sander I.; Lotz A.; Neumann H. D.; Czibor C.; Flagge A.; Zahradnik E.; Raulf M.;

  • 作者单位

    Institute for Prevention and Occupational MedicineInstitute of the Ruhr‐Universit?t Bochum (IPA;

    Institute for Prevention and Occupational MedicineInstitute of the Ruhr‐Universit?t Bochum (IPA;

    German Social Accident Insurance Institution for the public sector in North Rhine‐WestphaliaD;

    Institute for Prevention and Occupational MedicineInstitute of the Ruhr‐Universit?t Bochum (IPA;

    Institute for Prevention and Occupational MedicineInstitute of the Ruhr‐Universit?t Bochum (IPA;

    Institute for Prevention and Occupational MedicineInstitute of the Ruhr‐Universit?t Bochum (IPA;

    Institute for Prevention and Occupational MedicineInstitute of the Ruhr‐Universit?t Bochum (IPA;

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  • 正文语种 eng
  • 中图分类 医学免疫学;
  • 关键词

    Allergen exposure; Can f 1; domestic mites; Fel d 1; Mus m 1;

    机译：过敏原暴露;可以f 1;家用螨虫;母螨1;mus m 1;

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