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首页> 外文期刊>Allergy >New European Academy of Allergy and Clinical Immunology definition on pollen season mirrors symptom load for grass and birch pollen‐induced allergic rhinitis
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New European Academy of Allergy and Clinical Immunology definition on pollen season mirrors symptom load for grass and birch pollen‐induced allergic rhinitis

机译：新的欧洲过敏院和临床免疫学定义花粉季节镜子症状负荷为草和桦树花粉诱导的过敏性鼻炎

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摘要

Abstract Background The use of allergen immunotherapy ( AIT ) for allergic rhinitis and its clinical efficacy in clinical trials depends on the effective determination of pollen allergen exposure time periods. We evaluate pollen data from Germany to examine the new definitions on pollen season and peak pollen period start and end as proposed by the European Academy of Allergy and Clinical Immunology ( EAACI ) in a recently published Position Paper. The aim was to demonstrate the ability of these definitions to mirror symptom loads for grass and birch pollen‐induced allergic rhinitis based on real‐life data. Methods Data coming from four pollen monitoring stations in the Berlin and Brandenburg area in Germany and for 3?years (2014‐2016) were used to investigate the correlation of season definitions, birch and grass pollen counts and total nasal symptom and mediation scores as reported by patients in “Patients Hay fever Diaries” ( PHD s). After the identification of pollen periods on the basis of the EACCI criteria, a statistical analysis was employed, followed by a detailed graphical investigation. Results The analysis revealed that the definitions of pollen season as well as peak pollen period start and end as proposed by the EAACI are correlated to symptom loads for grass and birch pollen‐induced allergic rhinitis reported by patients in PHD s. Conclusion Based on our analysis, the validity of the EAACI definitions on pollen season is confirmed. Their use is recommended in future clinical trials on AIT as well as in daily routine for optimal patient care.
机译：摘要背景，过敏原免疫疗法（AIT）用于过敏性鼻炎及其临床试验的临床疗效取决于花粉过敏原暴露时间段的有效测定。我们评估德国的花粉数据，以研究欧洲过敏和临床免疫学（EAACI）在最近公布的位置纸上提出的投票季节和峰花粉时期的新定义。目的是展示这些定义对草和桦树花粉诱导的过敏性鼻炎的症状载荷的能力，基于现实生活数据。方法采用德国柏林和勃兰登堡地区的四个花粉监测站和3年（2014-2016）的数据用于调查季节定义，桦树和草花粉的相关性和报告的总鼻腔症状和调解分数通过患者在“患者花粉热日记”（PHD S）。在基于EACCI标准的基础上识别花粉期后，采用统计分析，其次是详细的图形调查。结果分析显示，eAaci提出的花粉季节以及峰花粉时期开始和结束的定义与博士学位患者报告的草和桦树花粉诱导的过敏性鼻炎的症状载荷相关。结论基于我们的分析，确认了对花粉季节的EAACI定义的有效性。在AIT的未来临床试验中建议使用它们，以及日常生活中的最佳患者护理。

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  • 来源
    《Allergy》 |2018年第9期|共9页
  • 作者

    Karatzas K.; Katsifarakis N.; Riga M.; Werchan B.; Werchan M.; Berger U.; Pfaar O.; Bergmann K.‐C.;

  • 作者单位

    Environmental Informatics Research GroupAristotle UniversityThessaloniki Greece;

    Environmental Informatics Research GroupAristotle UniversityThessaloniki Greece;

    Environmental Informatics Research GroupAristotle UniversityThessaloniki Greece;

    German Pollen Information Service FoundationBerlin Germany;

    German Pollen Information Service FoundationBerlin Germany;

    Aerobiology and Pollen Information Research UnitMedical University of ViennaVienna Austria;

    Department of Otorhinolaryngology Head and Neck SurgeryHeidelberg UniversityMannheim Germany;

    German Pollen Information Service FoundationBerlin Germany;

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  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类 医学免疫学;
  • 关键词

    allergic rhinitis; pollen counts; pollen season definition; symptom onset; symptom variation;

    机译：过敏性鼻炎;花粉计数;花粉季节定义;症状发作;症状变异;

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