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Secondary prevention measures in anaphylaxis patients: Data from the anaphylaxis registry

机译:过敏患者中的二级预防措施:来自过敏反应登记处的数据

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Abstract Background Patients with a history of anaphylaxis are at risk of future anaphylactic reactions. Thus, secondary prevention measures are recommended for these patients to prevent or attenuate the next reaction. Methods Data from the Anaphylaxis Registry were analyzed to identify secondary prevention measures offered to patients who experienced anaphylaxis. Our analysis included 7788 cases from 10 European countries and Brazil. Results The secondary prevention measures offered varied across the elicitors. A remarkable discrepancy was observed between prevention measures offered in specialized allergy centers (84% of patients were prescribed adrenaline autoinjectors following EAACI guidelines) and outside the centers: Here, EAACI guideline adherence was only 37%. In the multivariate analysis, the elicitor of the reaction, age of the patient, mastocytosis as comorbidity, severity of the reaction, and reimbursement/availability of the autoinjector influence physician's decision to prescribe one. Conclusions Based on the low implementation of guidelines concerning secondary prevention measures outside of specialized allergy centers, our findings highlight the importance of these specialized centers and the requirement of better education for primary healthcare and emergency physicians.
机译:摘要背景患者过敏症的患者面临未来过敏反应的风险。因此,推荐用于这些患者的二级预防措施,以防止或衰减下一个反应。方法分析了来自过敏反应登记商的数据,以确定向经历过敏反应的患者提供的二级预防措施。我们的分析包括来自10个欧洲国家和巴西的7788例。结果在eLitoroms中提供的二级预防措施。在专业过敏中心提供的预防措施之间观察到了显着的差异(84%的患者在EAACI指南之后规定了肾上腺素自身吸入器)和中心之外:在这里,EAACI准则遵守只有37%。在多变量分析中,患者的反应的引导者,患者的年龄,乳细胞症作为合并症,反应的严重程度,以及自动注射器的报销/可用性影响医生的决定规定规定的决定。结论基于较低实施关于专业过敏中心外的二级预防措施的指南,我们的调查结果强调了这些专业中心的重要性以及对初级医疗保健和急诊医生的更好教育要求。

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