• 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>ACS catalysis >Recent Advances in Transition-Metal-Catalyzed Synthetic Transformations of Organosilicon Reagents
【24h】

Recent Advances in Transition-Metal-Catalyzed Synthetic Transformations of Organosilicon Reagents

机译：过渡金属催化的有机硅试剂的合成转化的最新进展

获取原文
获取原文并翻译 | 示例
       
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Organosilicon compounds act as a nucleophile upon activation by an appropriate base and behave in a manner similar to main-group organometallic reagents. In the last decades, structurally divergent organosilicon reagents are available and have become more employed for synthetic transformation with the aid of transition-metal complexes, because organosilicon compounds are in general superior to other organometallic compounds in view of stability, solubility, nontoxicity, and easy-handling. Particularly, cross-coupling of organosilicon reagents with organic halides or pseudohalides has been considered to be a useful tool for constructing the carbon frameworks of various target molecules such as pharmaceuticals and pi-conjugated functional materials. Perfluoroalkylsilicon compounds such as CF3SiEt3 have found use as reagents for the metal-catalyzed introduction of perfluoroalkyl groups into many substrates. In addition, functionalized organosilicon reagents are readily accessible by catalytic approach starting with appropriate hydrocarbons such as alkenes, alkynes, alkanes, and arenes. This article reviews recent advances in transition metal-catalyzed transformations of organosilicon reagents according to the type of synthetic transformation and metal catalyst.
机译：有机硅化合物在通过适当的基础上活化时作为亲核试剂，并以类似于主组有机金属试剂的方式行事。在过去的几十年中，结构性不同的有机硅试剂可获得并且借助于过渡 - 金属配合物更加用于合成转化，因为有机硅化合物在稳定性，溶解度，无毒性和容易方面是优于其他有机金属化合物。屁股。特别地，有机硅氧烷与有机卤化物或伪卤化物的交叉偶联被认为是构建各种靶分子的碳框架，例如药物和PI缀合的官能材料的有用工具。诸如CF3Siet3的全氟烷基硅烷化合物已发现用作金属催化的全氟烷基的试剂中的用于许多基材。此外，通过以合适的烃如烯烃，炔，烷烃和芳烃开始，官能化有机硅氧烷试剂易于通过催化方法易于获得。本文根据合成转化和金属催化剂的类型，综述了有机硅试剂的过渡金属催化转化的最近进展。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号