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首页> 外文期刊>Acta Neurochirurgica >Spontaneous speech of patients with gliomas in eloquent areas before and early after surgery
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Spontaneous speech of patients with gliomas in eloquent areas before and early after surgery

机译:术前和术后早期口部区域神经胶质瘤患者的自发性言语

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Background: Glioma patients often complain about problems in daily conversation. A detailed spontaneous speech analysis could provide more insight in these communicative problems; no previous studies are reported. Objective: To select sensitive parameters in spontaneous speech pre- and post-operatively in patients with gliomas in eloquent areas. Methods: We included 27 patients and 21 healthy controls. In addition to a naming and category fluency test, spontaneous speech was collected 1 month pre-operatively and 3 months post-operatively, and analysed with the variables: Self-corrections, Repetitions, Lexical Diversity, Incomplete Sentences and Mean Length of Utterance (MLUw). A correlation analysis was performed between the linguistic variables and tumour characteristics (grade, localisation and volume), treatment related factors, and between the linguistic variables and the language tasks. Results: Pre-operatively, patients produced more Incomplete Sentences than the controls (p < 0.001). Post-operatively, patients' utterance length (MLUw) (p < 0.05) was also deviant. The quality of the spontaneous speech was influenced by tumour grade and localisation. There was no influence of tumour volume or treatment-related factors. Pre- and post-operatively, patients' performance on the naming and the fluency task deviated from normal (p < 0.001). The majority of the linguistic variables did not correlate with the language tasks, pointing to a measurement of distinct linguistic aspects. Conclusion: Pre- and post-operatively there was a disorder in naming, category fluency and spontaneous speech, partly influenced by tumour characteristics. A spontaneous speech analysis appeared to be a valuable addition to standardised language tasks. Both measurements are important tools to obtain a complete linguistic profile.
机译:背景:脑胶质瘤患者经常抱怨日常谈话中出现问题。详细的自发语音分析可以提供对这些交际问题的更多见解;没有先前的研究报道。目的:选择雄辩地区脑胶质瘤患者术前和术后言语敏感参数。方法:我们纳入了27位患者和21位健康对照。除命名和类别流利度测试外,术前1个月和术后3个月收集自发性言语,并使用以下变量进行分析:自我更正,重复,词法多样性,不完整句子和平均言语时长(MLUw) )。在语言变量和肿瘤特征(等级,位置和体积),治疗相关因素之间以及语言变量和语言任务之间进行了相关分析。结果:术前,患者产生的不完整句子多于对照组(p <0.001)。术后患者的话语长度(MLUw)(p <0.05)也有差异。自发语音的质量受肿瘤等级和位置的影响。没有肿瘤体积或治疗相关因素的影响。术前和术后,患者在命名和流利度任务上的表现均偏离正常(p <0.001)。大多数语言变量与语言任务不相关,这表明对不同语言方面的度量。结论:手术前后存在命名障碍,类别流利度和自发性言语障碍,部分受肿瘤特征的影响。自发的语音分析似乎是标准化语言任务的宝贵补充。两种测量都是获得完整语言概况的重要工具。

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