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首页> 外文期刊>Acta neurologica Scandinavica. >Cerebral hemodynamic changes at basilar artery in patients with obstructive sleep apnea syndrome. A case-control study
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Cerebral hemodynamic changes at basilar artery in patients with obstructive sleep apnea syndrome. A case-control study

机译：阻塞性睡眠呼吸暂停综合征患者基底动脉的脑血流动力学变化。病例对照研究

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Introduction: Obstructive sleep apnea syndrome (OSAS) is characterized in polysomnography by recurrent airflow obstruction during sleep. The underlying pathogenic mechanisms of neuropsychological and cerebrovascular events in patients with OSAS have not been clarified unequivocally. Material and methods: Case-control study to evaluate the cerebral vasomotor reactivity assessed by breath-holding maneuver at basilar artery in patients with OSAS compared to control subjects. Results: The study included 76 patients with OSAS and 76 controls. Vascular risk factors (arterial hypertension, diabetes mellitus, hypercholesterolemia, smoking), age, gender, coronary, and peripheral arterial diseases were similar in both groups. Patients with OSAS had breath-holding test values (31.9 ± 13.35%) lower than controls (39.06 ± 13.16%), (P = 0.001). Patients with OSAS had higher systolic and diastolic blood pressure both basal and apnea and also a higher basal heart rate. Conclusions: Altered cerebral hemodynamics together with increased blood pressure values in patients with OSAS may play a role in the association between this disease and the development of cerebrovascular events. This implies that this disease should be identified through guide symptoms such as snoring, sleep apnea, and daytime sleepiness in all patients who consult for these symptoms to reduce the number of cerebrovascular events.
机译：简介：阻塞性睡眠呼吸暂停综合症（OSAS）在多导睡眠图上的特征是睡眠期间反复出现气流阻塞。尚未明确阐明OSAS患者的神经心理学和脑血管事件的潜在致病机制。材料和方法：病例对照研究，通过与对照组相比，评价了通过OSAS患者在基底动脉进行屏气操作评估的脑血管舒缩反应性。结果：该研究包括76例OSAS患者和76例对照。两组的血管危险因素（动脉高血压，糖尿病，高胆固醇血症，吸烟），年龄，性别，冠状动脉和外周动脉疾病相似。 OSAS患者的屏气测试值（31.9±13.35％）比对照组（39.06±13.16％）低（P = 0.001）。 OSAS患者的基础和呼吸暂停的收缩压和舒张压均较高，基础心率也较高。结论：OSAS患者的脑血流动力学改变以及血压升高可能与该疾病与脑血管事件的发展有关。这意味着在所有咨询这些症状以减少脑血管事件数量的患者中，应通过打guide，睡眠呼吸暂停和白天嗜睡等指导症状来识别该疾病。

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