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首页> 外文期刊>Animal Science Journal >Identification of sialyl oligosaccharides including an oligosaccharide nucleotide in colostrum of an addax (Addax nasomaculatus) (Subfamily Antelopinae)
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Identification of sialyl oligosaccharides including an oligosaccharide nucleotide in colostrum of an addax (Addax nasomaculatus) (Subfamily Antelopinae)

机译:鉴定唾液酸寡糖的唾液酸寡糖(Addax Nasomaculatus)(亚家族抗ovinae)

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摘要

Mammalian milk/colostrum usually contains milk oligosaccharides along with the predominant lactose. Although milk oligosaccharides of a variety of Bovidae species including cow, sheep and goat have been characterized, those of the addax, an Antelopinae species of the Bovidae, have not as yet been clarified. In this study, several sialyl oligosaccharides were purified from a sample of addax colostrum and characterized as follows: Neu5Ac(2-8)Neu5Ac(2-3)Gal(1-4)Glc, Neu5Gc(2-8)Neu5Gc(2-3)Gal(1-4)Glc, Neu5Ac(2-3)Gal(1-4)Glc, Neu5Ac(2-6)Gal(1-4)GlcNAc, Neu5Gc(2-3)Gal(1-4)Glc, Neu5Gc(2-6)Gal(1-4)Glc, Neu5Gc(2-6)Gal(1-4)GlcNAc. In addition, an oligosaccharide nucleotide Neu5Gc(2-6)Gal(1-4)GlcNAc1-UDP was characterized. Molecular species of a variety of sialyl oligosaccharides found in milk and colostrum of these Bovidae were compared.
机译:哺乳动物牛奶/初乳通常含有牛奶寡糖以及主要的乳糖。 虽然牛奶寡糖包括牛,羊和山羊在内的各种Bovidae物种的特征,但果酱的Addax含量,肉豆蔻酸碱物种尚未澄清。 在该研究中,从Addax Colostrum的样品中纯化了几种SiaLyl寡糖,其特征如下:Neu5ac(2-8)Neu5ac(2-3)Gal(1-4)Glc,Neu5GC(2-8)Neu5GC(2- 3)GAL(1-4)GLC,NEU5AC(2-3)GLC(1-4)GLC,NEU5AC(2-6)GAL(1-4)GLCNAC,NEU5GC(2-3)GAL(1-4) GLC,NEU5GC(2-6)GAL(1-4)GLC,NEU5GC(2-6)GAL(1-4)GLCNAC。 另外,表征了寡糖核苷酸Neu5GC(2-6)GAL(1-4)GLCNAC1-UDP。 比较了这些牛奶和初乳的各种唾液酸寡糖的分子种。

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