• 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Annals of allergy, asthma, and immunology >OTIC AND NASAL POLYPS WITH PERIPHERAL EOSINOPHILIA AND BILATERAL HEARING LOSS
【24h】

OTIC AND NASAL POLYPS WITH PERIPHERAL EOSINOPHILIA AND BILATERAL HEARING LOSS

机译：含有外周嗜酸性粒细胞和双边听力损失的ONT和鼻息肉

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

IntroductionRefractory otitis media (OM) in adults is challenging as misdiagnosis can lead to permanent sensorineural hearing loss. OM in the presence of peripheral eosinophilia and atopic history should warrant alternative treatment rather than antibiotics and topical steroids. Case DescriptionA 71-year-old female with asthma, nasal polyps and allergic rhinitis presented with two years of bilateral hearing loss. She had multiple episodes of recurrent otitis media treated with topical and systemic steroids along with antibiotics without improvement. Physical exam was significant for hypertrophied turbinates and anterior rhinoscopy showed a large polyp in the right middle meatus. Otoendoscopy showed a right tympanic membrane with chronic myringitis, central perforation with polypoid changes to the middle ear mucosa. Left tympanic membrane had central perforation and polypoid tissue (Figure 1). Labs were significant for peripheral eosinophilia of 1.3?×?103eosinophils/μL (16.7%) and IgE level of 1065 IU/mL. A diagnosis of presumed eosinophilic otitis media was made. DiscussionEosinophilic otitis media (EOM) is a rare disorder of intractable bilateral otitis media. Diagnosis can be made using the major criteria of eosinophils in the middle ear mucosa or its effusion, along with two or more items of the minor criteria (association with asthma, nasal polyposis, chronic rhinosinusitis, resistance to conventional treatment for otitis media, and a highly viscous middle ear effusion). The differential should exclude disorders such as eosinophilic granulomatosis with polyangiitis and hypereosinophilic syndrome. Treatment of EOM includes removal of eosinophilic middle ear effusion and suppression with steroids.
机译：由于误诊可能导致永久性感觉听力损失，成人中的引入细胞炎培养基（OM）挑战。在外周嗜酸性粒细胞和特应历史存在下的OM应该需要替代治疗而不是抗生素和局部类固醇。案例描述71岁女性患有哮喘，鼻息肉和过敏性鼻炎，具有两年的双边听力损失。她患有多次肠炎培养基，用局部和全身类固醇治疗，以及抗生素没有改善。体育考试对于肥大鼻蛋白和前鼻腔镜片显示出右侧中间的脊髓型显示出大息肉。耳鼻镜检查显示出具有慢性流动性的右鼓膜膜，中耳粘膜的息肉膜的中心穿孔。左鼓膜膜具有中央穿孔和息肉组织（图1）。实验室对于1.3？×1032粒细胞/μl（16.7％）和1065IU / ml的IgE水平的实验室是重要的。制造了推定嗜酸性粒细胞性中耳炎的诊断。讨论氨基粒细胞介质（EOM）是一种难以致密的双侧中耳炎的罕见疾病。可以使用中耳粘膜或其积液中的嗜酸性粒细胞的主要标准进行诊断，以及次要标准的两个或更多项或与哮喘，鼻息蛋白，慢性鼻窦炎，对中耳炎的常规治疗的患者的两个或更多项高度粘稠的中耳积液）。差异应排除疾病，例如嗜酸性粒细胞粒细胞瘤，具有多苯炎和过嗜合体综合征。 EOM的治疗包括去除嗜酸性中耳积液和类固醇的抑制。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号