Rapid onset of effect of benralizumab on morning peak expiratory flow in severe, uncontrolled asthma

Chupp Geoffrey; Lugogo Njira L.; Kline Joel N.; Ferguson Gary T.; Hirsch Ian; Goldman Mitchell; Zangrilli James G.; Trudo Frank

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Rapid onset of effect of benralizumab on morning peak expiratory flow in severe, uncontrolled asthma

机译：迅速发作了北欧司布对早期峰值呼气流动的严重，不受控制的哮喘

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Background: Benralizumab is a unique eosinophil-depleting monoclonal antibody that significantly reduces asthma exacerbations, improves lung function and asthma symptoms, and permits the reduction of maintenance oral corticosteroid dosage for patients with severe, uncontrolled eosinophilic asthma.

机译：背景：Benralizumab是一种独特的嗜酸性粒细胞耗尽单克隆抗体，可显着降低哮喘发作，提高肺功能和哮喘症状，并允许减少严重，不受控制的嗜酸性哮喘患者的维持口服皮质类固醇剂量。

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《Annals of allergy, asthma, and immunology》 |2019年第5期|共8页
作者
Chupp Geoffrey; Lugogo Njira L.; Kline Joel N.; Ferguson Gary T.; Hirsch Ian; Goldman Mitchell; Zangrilli James G.; Trudo Frank;
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作者单位

Yale Ctr Asthma &

Airway Dis 300 Cedar St New Haven CT 06510 USA;

Univ Michigan Med Ctr Ann Arbor MI 48109 USA;

Univ Iowa Carver Coll Med Iowa City IA USA;

Pulm Res Inst Southeast Michigan Farmington Hills MI USA;

AstraZeneca Gaithersburg MD USA;

AstraZeneca Gaithersburg MD USA;

AstraZeneca Gaithersburg MD USA;

AstraZeneca Delaware OH USA;

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正文语种 eng
中图分类医学免疫学;
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1. Rapid onset of effect of benralizumab on morning peak expiratory flow in severe, uncontrolled asthma [J] . Chupp Geoffrey, Lugogo Njira L., Kline Joel N., Annals of allergy, asthma, and immunology . 2019,第5期

机译：迅速发作了北欧司布对早期峰值呼气流动的严重，不受控制的哮喘
2. Rates of Change in Peak Expiratory Flow and in Diurnal Variation in Peak Flow in Patients Recovering from Acute Severe Asthma [J] . G. E. Packe, Ruth M. Cayton, W. Freeman Clinical Science . 1994,第1期

机译：从急性重症哮喘中康复的患者的呼气峰值流量变化和峰值流量的昼夜变化率
3. Nocturnal waking and morning dip of peak expiratory flow in clinically stable asthma patients during treatment. Occurrence and patient characteristics. [J] . Van Keimpema AR, Ariaansz M, Tamminga JJ, Respiration: International Review of Thoracic Diseases . 1997,第1期

机译：临床稳定的哮喘患者在治疗期间的夜间醒来和呼气高峰高峰的早晨下降。发生率和患者特征。
4. Yoga Pranayama Increases Peak Expiratory Flow (PEF) in Patient with Asthma [C] . Made Mahaguna Putra, Sriyono, Deni Yasmara International Nursing Conference on Education, Practice and Research Development in Nursing . 2017

机译：Yoga Pranayama在哮喘患者中增加了峰值呼气流（PEF）
5. Peak expiratory flow rates in German children exposed to ambient outdoor air pollution, particulate matter and trace elements. [D] . Asakevich, Scott Alan. 2006

机译：暴露于外界室外空气污染，颗粒物和微量元素的德国儿童的呼气峰值流速。
6. Onset of Effect Changes in Airflow Obstruction and Lung Volume and Health-Related Quality of Life Improvements with Benralizumab for Patients with Severe Eosinophilic Asthma: Phase IIIb Randomized Controlled Trial (SOLANA) [O] . Reynold A Panettieri, Jr, Tobias Welte, 2020

机译：贝拉珠单抗对严重嗜酸性粒细胞性哮喘患者的发作气流阻塞和肺体积的变化以及与健康有关的生活质量改善：IIIb期随机对照试验（SOLANA）
7. Rapid onset of effect of benralizumab on morning peak expiratory flow in severe, uncontrolled asthma [O] . Geoffrey Chupp, Njira L. Lugogo, Joel N. Kline, 2019

机译：在严重，不受控制的哮喘中迅速发作了北高峰呼气流量的效果

Rapid onset of effect of benralizumab on morning peak expiratory flow in severe, uncontrolled asthma

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