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首页> 外文期刊>ANZ journal of surgery >Metastatic cutaneous squamous cell carcinoma of the scalp.
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Metastatic cutaneous squamous cell carcinoma of the scalp.

机译：头皮的转移皮肤鳞状细胞癌。

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BACKGROUND: Metastatic cutaneous squamous cell carcinoma arising from the scalp, although relatively uncommon, is associated with a poor outcome. Older men with a history of baldness and actinic scalp lesions are particularly at risk. METHODS: Between 1980 and 2005, 27 patients with metastatic cutaneous squamous cell carcinoma of the scalp were referred to the Head and Neck Cancer Service at Westmead Hospital, Sydney. Relevant data were extracted from a prospectively maintained database. Patterns of recurrence and outcome were analysed. RESULTS: Median age at diagnosis was 70 years and median follow up was 45 months in 26 men and one woman. Ten primary (index) lesions were located on the midline scalp, 14 left sided and 3 right sided. Median lesion size was 18 mm and median thickness was 5.5 mm. The median time between treatment of the scalp primary and the development of nodal metastases was 8 months. In 10 patients, nodal metastases were present at the time of primary treatment. Fifteen patients developed parotid metastases (+cervical nodes in 7 of 15) and 12 developed cervical only metastases (5 of 12 level V). All patients underwent nodal surgery and most (75%) also received adjuvant radiotherapy. At the last follow up, 41% of patients had died from their disease. Median survival after relapse was 9 months and all patients experiencing relapse died with most (11 of 13) dying from metastatic disease. CONCLUSION: Patients with metastatic cutaneous squamous cell carcinoma of the scalp have a poor prognosis with most dying from regional relapse. Those treated with surgery and adjuvant radiotherapy had a better outcome.
机译：背景：虽然相对不常见，但虽然较差，但虽然较差，但虽然与差的结果有关。具有秃头和光化头皮病史的老年人特别有风险。方法：1980年至2005年间，27例悉尼西部医院的头部和颈部癌症服务中的27例转移皮肤鳞状细胞癌。从前瞻性维护的数据库中提取相关数据。分析了复发和结果的模式。结果：诊断中位年龄为70岁，26名男子和一个女人在25个月的中位数。 10个主要（指数）病变位于中线头皮，14个左侧和3个右侧。中位数病变尺寸为18毫米，中间厚度为5.5毫米。治疗头皮初级和节点转移的发展之间的中​​位时间为8个月。在10名患者中，在初级治疗时存在节点转移。十五名患者开发了腮腺转移（+宫颈节点，在15个中的7个）和12个癌症的宫颈仅转移（5个级V）。所有患者均接受淋巴结手术和大多数（75％）也接受了佐剂放射治疗。在最后一次跟进，41％的患者从他们的疾病中死亡。复发后的中位存活是9个月，所有经历复发的患者都死于大多数（11分中）从转移性疾病中死亡。结论：转移皮肤鳞状细胞癌的患者的头皮预后具有差的预后差，从区域复发最染色。用手术治疗的人和佐剂放射治疗有更好的结果。

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