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首页> 外文期刊>Archives of cardiovascular diseases. Supplements >Dietary fibre intake and mortality from cardiovascular disease and all cancers: A meta-analysis of prospective cohort studies
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Dietary fibre intake and mortality from cardiovascular disease and all cancers: A meta-analysis of prospective cohort studies

机译：来自心血管疾病的膳食纤维摄入和死亡率和所有癌症：预期队列研究的荟萃分析

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Summary Background. — Accumulating evidence supports health benefits of dietary fibre, such as improving lipid profiles, lowering blood pressure and improving insulin sensitivity, but evidence from comprehensive investigation of dietary fibre intake and mortality from cardiovascular disease (CVD) and all cancers is limited. Aims. - To quantitatively assess the association between dietary fibre intake and mortality from CVD and all cancers. Methods. - We performed a meta-analysis of prospective cohort studies. Eligible studies were identified by searching PubMed and Embase databases for all articles published up to September 2014 and via hand searching. Study-specific estimates adjusting for potential confounders were combined to calculate pooled relative risks (RRs) with 95% confidence intervals (CIs), using a random-effects model. Results. - We found 15 studies that examined the association between dietary fibre and mortality from CVD, coronary heart disease (CHD) and all cancers. The pooled RRs of CVD, CHD and all-cancer mortality for the highest versus lowest category of dietary fibre were 0.77 (95% Cl: 0.71-0.84), 0.76 (95% Cl: 0.67-0.87) and 0.86 (95% Cl: 0.79-0.93), respectively. In a dose-response meta-analysis, the pooled RRs for an increment of 10 g/day in dietary fibre intake were 0.91 (95% Cl: 0.88-0.94) for CVD, 0.89 (95% Cl: 0.85-0.93) for CHD and 0.94 (95% Cl: 0.91-0.97) for all cancers. Conclusions. — Our findings suggest that high dietary fibre intake is associated with a reduced risk of mortality from CVD and all cancers. These results support the current recommendation that high dietary fibre intake should be part of a healthy diet.
机译：摘要背景。 - 积累证据支持膳食纤维的健康益处，例如改善脂质谱，降低血压和提高胰岛素敏感性，但是从膳食纤维摄入量和心血管疾病（CVD）的死亡率综合调查的证据是有限的。目标。 - 定量评估来自CVD和所有癌症的膳食纤维摄入和死亡率之间的关联。方法。 - 我们对预期队列研究进行了荟萃分析。通过搜索2014年9月和手中搜索的所有文章的PubMed和Embase数据库来确定符合条件的研究。使用随机效应模型，组合了对潜在混淆的调整以计算池相对风险（CIS）的汇集相对风险（RRS）。结果。 - 我们发现15项研究，检查了CVD，冠心病（CHD）和所有癌症的膳食纤维和死亡率之间的关系。最高的CVD，CHD和全癌死亡率的汇集RR为最高，最低类别膳食纤维为0.77（95％CL：0.71-0.84），0.76（95％CL：0.67-0.87）和0.86（95％CL： 0.79-0.93）分别。在剂量 - 反应META分析中，CVD的膳食纤维摄入量为10克/天的增量10克/天的汇集RRS为CVD，0.89（95％CL：0.85-0.93）进行CHD的0.91（95％CL：0.88-0.94）所有癌症的0.94（95％Cl：0.91-0.97）。结论。 - 我们的研究结果表明，高膳食纤维摄入量与CVD和所有癌症的死亡风险降低有关。这些结果支持当前建议，即高膳食纤维摄入应该是健康饮食的一部分。

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