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首页> 外文期刊>ASAIO journal >Clinical Significance of Early Hospital Readmission in Continuous-Flow Left Ventricular Assist Device Patients
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Clinical Significance of Early Hospital Readmission in Continuous-Flow Left Ventricular Assist Device Patients

机译：连续流动左心室辅助装置患者早期医院阅览的临床意义

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Data on the clinical significance of early hospital readmission within 90 days following left ventricular assist device (LVAD) implantation in patients with continuous-flow LVAD are limited. We aimed to assess the incidence, predictors, and outcomes of 90-day readmission in LVAD patients. Hospital readmission or death was assessed within 90 days after hospital discharge in 177 patients with HeartMate II LVADs implanted between May 2008 and June 2014. Predictors of early readmission and risk of death were evaluated using multivariable Cox models following adjustment for clinical covariates. Hospital readmission or death rate was 37% within 90 days. Age at implantation (hazard ratio [HR] = 1.03 per 1 year increase,p= 0.016), diabetes (HR = 2.19,p= 0.031) and smoking at baseline (HR = 2.06,p= 0.034) predicted early hospital readmission, while a higher baseline body mass index was found to be protective (HR = 0.92 per each unit increase in body mass index,p= 0.003). One-year all-cause mortality was 19% in patients with early hospital readmission as compared to 1% with no early hospital readmission (HR 15.50,p= 0.01). One-year mortality was 35% in patients with 2 or more readmissions compared to 10% mortality in patients with one readmission and 1% mortality in patients with no readmissions (p< 0.001). In LVAD patients, there is a high incidence of hospital readmission within 90 days, which is associated with an increased mortality. Targeted interventions, such as closer follow-up to prevent early and recurrent hospital readmissions in LVAD recipients, are warranted to improve outcomes.
机译：左心室辅助装置（LVAD）植入连续流动LVAD患者的90天内早期医院入睡临床意义的数据有限。我们的旨在评估LVAD患者90天休息的发病率，预测因子和结果。在2008年5月至2014年5月期间植入的177例HeartMate II Lvads患者的90天内评估了医院入院或死亡。使用多变量COX模型进行临床协变量后，评估早退的预测和死亡风险的预测因素。医院入院或死亡率在90天内为37％。植入年龄（危险比[HR] = 1.03每1年增加，P = 0.016），糖尿病（HR = 2.19，P = 0.031），并在基线吸烟（HR = 2.06，P = 0.034）预测早期医院入院发现较高的基线体重指数是保护性的（每个单位每个单位的HR = 0.92增加体重指数，P = 0.003）。早期医院住院患者的一年内的死亡率为19％，而1％的患者没有早期医院入院（HR 15.50，P = 0.01）。一年的死亡率为2例或以上的预留患者35％，而1名患者的10％死亡率和1％的死亡率和没有入院患者的死亡率（P <0.001）。在LVAD患者中，90天内医院入院的发病率很高，死亡率增加了。有针对性的干预措施，例如更紧密的后续行动，以防止在LVAD受体中的早期和经常性医院入院，以改善结果。

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