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Quantification and Analysis of Leaflet Flutter on Biological Prosthetic Cardiac Valves

机译：生物假肢心脏瓣膜传单颤动的量化与分析

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摘要

The use of porcine or bovine pericardium biological cardiac valves has as its main disadvantage a relatively short lifespan, with failures due to calcification and fatigue. Increasing these valves' durability constitutes a great challenge. An understudied phenomenon is the effect of flutter, an oscillation of the leaflets that can cause regurgitation and accelerate calcification and fatigue. As a starting point to study how to reduce or prevent these oscillations, a method was developed to quantify the flutter frequencies occurring at the point of the valve's full opening. On a test bench that simulates the heart flow, the cusp behaviors of eight biological valves were filmed with a high speed camera at 2000 frames per second at different flow rates and motion capture software obtained the frequencies and amplitudes of the vibrations of each leaflet. Oscillations in the range of 200 Hz with average amplitudes of 0.4 mm were found; larger nominal diameter valves obtained lower values, and bovine pericardial valves had superior performance compared to porcine valves. A dimensionless analysis was performed to find a relationship between the geometric and mechanical properties of the valves with the critical speed of the onset of fluttering. This relationship inspired a method to predict whether flutter will occur in the bioprosthesis. This method is a new tool for the consideration of maximizing the life of prosthetic valves.
机译：使用猪或牛心包生物心脏瓣膜具有相对较短的寿命的主要缺点，由于钙化和疲劳导致的故障。增加这些阀门的耐用性构成了巨大的挑战。被清算的现象是颤动的效果，传单的振动振动，这会导致反流性并加速钙化和疲劳。作为研究如何减少或防止这些振荡的起点，开发了一种方法来量化在阀门的全开口点处发生的颤动频率。在模拟心脏流量的测试台上，在不同流速的2000秒框架上用高速摄像机拍摄八个生物阀的尖端行为，并且运动捕获软件获得了每个宣传叶的振动的频率和幅度。发现了200 Hz的振荡，每个具有0.4mm的平均幅度;较大的标称直径阀获得较低的值，与猪阀相比，牛心包阀的性能优异。执行无量纲分析，以找到阀门几何和机械性能之间的关系，其具有凸起的突出瞬态的临界速度。这种关系激发了一种方法来预测生物假期中是否会发生颤振。这种方法是考虑最大化假肢阀的寿命的新工具。

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