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首页> 外文期刊>Artificial Organs >Is Multiple Overlapping Uncovered Stents Technique Suitable for Aortic Aneurysm Repair?
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Is Multiple Overlapping Uncovered Stents Technique Suitable for Aortic Aneurysm Repair?

机译：是多重重叠的覆盖的支架技术，适用于主动脉瘤修复吗？

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Abstract A computational fluid dynamic model to assess the impact of flow‐diverter device on intra‐aneurysmal flow in complex aortic aneurysm from the viewpoint of hemodynamics is presented. The aim of this study is to investigate the hemodynamic effects of an endovascular flow‐diverter technique using multiple overlapping uncovered stents (MOUS) in the treatment of complex aortic aneurysm involving side branch. The placement of porous barrier such as MOUS across the aneurysm alters the blood flow pattern in the aneurysm sac. Subsequently, flow diversion effect creates a natural hemodynamic environment to promote aneurysm thrombosis, thus stabilizing the aneurysm. The study revealed that intra‐aneurysmal flow was reduced and low time average wall shear stress (TAWSS), high relative residence time (RRT), and high oscillatory shear index (OSI) regions were observed in the aneurysm sac. Three to four MOUS stents produced the best hemodynamic environment for the formation of thrombus, with saccular aneurysm performing better than fusiform aneurysm from the viewpoint of hemodynamics. A result also revealed that flow in the branch vessel was not compromised suggesting the capacity of preserving patency of branch vessels while at the same time stabilizing the aneurysm. Based on the hemodynamic performance of this study coupled with existing reported clinical studies, deploying three to four MOUS stents is a feasible solution to treat aneurysm with side branch, favorably for saccular shape aneurysm.
机译：摘要提出了一种计算流体动力学模型，从而提出了从血流动力学的观点出发，评估流动转向器装置对复杂主动脉瘤中的动脉瘤流动的影响。本研究的目的是研究使用多重重叠的覆盖支架（MOU）治疗涉及侧分支的复杂主动脉瘤的血管血管流动转向技术的血流动力学效应。在动脉瘤上的摩托屏蔽的诸如Mous的多孔屏障的位置改变了动脉瘤囊中的血液流动模式。随后，流动导流效应产生自然血液动力学环境，以促进动脉瘤血栓形成，从而稳定动脉瘤。该研究表明，在动脉瘤囊中观察到动脉内瘤流动减少，低时间平均壁剪切应力（Taws），高相对停留时间（RRT）和高振荡剪切指数（OSI）区域。三到四个慕的支架为血栓形成了最佳的血流动力学环境，从血流动力学的观点来看，囊状动脉瘤比梭形动脉瘤更好。结果还显示，分支容器中的流动不损害，表明在稳定动脉瘤的同时保持分支血管的通畅的能力。基于本研究的血流动力学性能与现有报告的临床研究相结合，部署了三到四个哑子支架是一种可行的解决方案，可以用侧枝治疗动脉瘤，有利地用于囊状动脉瘤。

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